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Details on Person Functional evaluation of PTEN missense mutations using in vitro phosphoinositide phosphatase assay

Class:Id	LiteratureReference:1889775
_displayName	Functional evaluation of PTEN missense mutations using in vitro phosphoinositide phosphatase assay
_timestamp	2011-11-01 11:28:07
author	[Person:448639] Han, SY [Person:177872] Kato, H [Person:190105] Kato, S [Person:380218] Suzuki, T [Person:549518] Shibata, H [Person:164204] Ishii, S [Person:879626] Shiiba, K [Person:194084] Matsuno, S [Person:207101] Kanamaru, R [Person:1889824] Ishioka, C
created	[InstanceEdit:1889922] Williams, MG, 2011-11-01
journal	Cancer Res
pages	3147-51
pubMedIdentifier	10866302
title	Functional evaluation of PTEN missense mutations using in vitro phosphoinositide phosphatase assay
volume	60
year	2000
(literatureReference)	[Reaction:1855205] I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol [Homo sapiens] [Pathway:2219528] PI3K/AKT Signaling in Cancer [Homo sapiens] [FailedReaction:2317387] PTEN cancer mutants do not dephosphorylate PIP3 [Homo sapiens] [Pathway:5674404] PTEN Loss of Function in Cancer [Homo sapiens] [EntityWithAccessionedSequence:2317339] PTEN R130G [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:2317416] PTEN R130Q [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:2317430] PTEN R130L [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:2317432] PTEN R130P [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:2317439] PTEN C124R [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:2317461] PTEN C124F [cytosol] [Homo sapiens] List all 42 refering instances
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