Reactome: A Curated Pathway Database
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Query author contributions in Reactome

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Details on Person Jassal, B, 2006-10-18 09:56:53

Class:IdInstanceEdit:188574
_displayNameJassal, B, 2006-10-18 09:56:53
_timestamp2008-11-19 13:59:53
author[Person:73447] Jassal, Bijay
dateTime2006-10-18 13:56:53
(created)[Summation:188572] GAB1 binds to EGF receptors via tyrosine autophosphorylation...
[Summation:188573] The adaptor protein CIN85 is monoubiquitinated by CBL after ...
[Person:188575] Shimokawa, N
[Summation:188576] Beta-Pix (Cool-1) associates with CBL, which appears to be a...
[Summation:188577] CBL binds multiple signalling proteins including GRB2. The C...
[Summation:188578] EGFR kinase phosphorylates the phosphorylation sites tyrosin...
[LiteratureReference:188579] Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors
[Summation:188580] Sprouty is ubiquitinated by CBL in an EGF-dependent manner. ...
(modified)[Complex:109798] GRB2-1:SOS1:p-Y427-SHC1 [cytosol] [Homo sapiens]
[Complex:177507] Activated TrkA receptor complex:Clathrin-coated vesicle:dynein:dynactin complex [plasma membrane] [Homo sapiens]
[Reaction:177930] GAB1 phosphorylation by EGFR kinase [Homo sapiens]
[Complex:182936] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:Ub-CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] [Homo sapiens]
[Pathway:182971] EGFR downregulation [Homo sapiens]
[Reaction:182986] CBL-mediated ubiquitination of CIN85 [Homo sapiens]
[Reaction:183052] CBL binds to GRB2 [Homo sapiens]
[Reaction:183084] CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix [Homo sapiens]
[Reaction:183089] CBL binds and ubiquitinates phosphorylated Sprouty [Homo sapiens]
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No pathways have been reviewed or authored by Jassal, B, 2006-10-18 09:56:53 (188574)