Query author contributions in Reactome
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Details on Person The guanine nucleotide exchange factor SOS1 interacts with E...
| Class:Id | Summation:188440 |
|---|---|
| _displayName | The guanine nucleotide exchange factor SOS1 interacts with E... |
| _timestamp | 2011-09-06 16:45:41 |
| created | [InstanceEdit:188436] Jassal, B, 2006-10-13 13:48:32 |
| modified | [InstanceEdit:188582] Jassal, Bijay, 2006-10-18 [InstanceEdit:1566990] Orlic-Milacic, Marija, 2011-09-06 |
| text | The guanine nucleotide exchange factor SOS1 interacts with EGFR through the adaptor protein, GRB2. Upon formation of this complex, SOS activates RAS by promoting GDP release and GTP binding. |
| (summation) | [Reaction:177938] SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) [Homo sapiens] [Reaction:9846404] GOCAM SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) [Homo sapiens] |
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No pathways have been reviewed or authored by The guanine nucleotide exchange factor SOS1 interacts with E... (188440)
