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Details on Person Foxo1 [nucleoplasm]
Class:Id EntityWithAccessionedSequence:187293
_displayName Foxo1 [nucleoplasm]
_timestamp 2018-09-26 16:41:57
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:187302] Tello-Ruiz, MK, 2006-09-13 01:14:23
endCoordinate 652
modified [InstanceEdit:189794] Tello-Ruiz, MK, 2006-12-01 23:20:56 [InstanceEdit:9621297] Orlic-Milacic, Marija, 2018-09-26
name Foxo1
referenceEntity [ReferenceGeneProduct:187291] UniProt:Q9R1E0 Foxo1 [Mus musculus]
species [Species:48892] Mus musculus
stableIdentifier [StableIdentifier:363104] R-MMU-187293.2
startCoordinate 1
(activeUnit) [PositiveGeneExpressionRegulation:9623044] Positive gene expression regulation by 'Foxo1:Agrp gene [nucleoplasm]' [NegativeGeneExpressionRegulation:9623086] Negative gene expression regulation by 'Foxo1:Pomc gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9625864] Positive gene expression regulation by 'Foxo1:Retn gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9627009] Positive gene expression regulation by 'Foxo1:Nr3c1:(ALDO1,11DCORST,CORST,CORT) dimer:Trim63 gene [nucleoplasm]'
(hasComponent) [Complex:9623041] Foxo1:Agrp gene [nucleoplasm] [Mus musculus] [Complex:9623082] Foxo1:Pomc gene [nucleoplasm] [Mus musculus] [Complex:9623229] Foxo1:Ppargc1a [nucleoplasm] [Mus musculus] [Complex:9625140] Foxo1:Sin3a:Hdac1,Hdac2 dimers [nucleoplasm] [Mus musculus] [Complex:9625853] Foxo1:Retn gene [nucleoplasm] [Mus musculus] [Complex:9627010] Foxo1:Nr3c1:(ALDO1,11DCORST,CORST,CORT) dimer:Trim63 gene [nucleoplasm] [Mus musculus]
(hasMember) [DefinedSet:9625439] Foxo1,Foxo3 [nucleoplasm] [Mus musculus]
(input) [Reaction:9623032] Foxo1 binds Agrp gene promoter [Mus musculus] [Reaction:9623061] Foxo1 binds Pomc gene promoter [Mus musculus] [Reaction:9623232] Foxo1 binds Ppargc1a [Mus musculus] [Reaction:9625109] Foxo1 and Sin3a:Hdac complex bind Gck gene promoter [Mus musculus] [Reaction:9625700] Foxo1 and Nr3c1 bind Trim63 gene promoter [Mus musculus] [Reaction:9625830] Foxo1 binds Retn gene [Mus musculus] [Reaction:9626944] CREBBP acetylates Foxo1 [Homo sapiens] [Reaction:9833493] p-T182 Mapkapk5 phosphorylates Foxo1 [Mus musculus]
(output) [BlackBoxEvent:9621559] Foxo1 mRNA translation is negatively regulated by miR-9-5p [Mus musculus] [Reaction:9626966] Sirt1 deacetylates Foxo1 [Mus musculus]
(physicalEntity) [CatalystActivity:187327] unknown activity of Foxo1 [nucleoplasm]
(regulator) [NegativeRegulation:190270] Negative regulation by 'foxo1 [nucleoplasm]' [NegativeRegulation:190274] Negative regulation by 'foxo1 [nucleoplasm]' [NegativeRegulation:190277] Negative regulation by 'foxo1 [nucleoplasm]' [PositiveRegulation:9621291] Positive regulation by 'foxo1 [nucleoplasm]'
(updatedInstance) [_UpdateTracker:9899702] Update Tracker - [EntityWithAccessionedSequence:187293] Foxo1 [nucleoplasm] - v67:[modifyEndCoordinate, modifyName]
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Pathways
No pathways have been reviewed or authored by Foxo1 [nucleoplasm] (187293)