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Details on Person UniProt:P01325 Ins1
Class:Id
ReferenceGeneProduct:187280
_chainChangeLog
signal peptide:1-24 added on Fri February 6 2015;peptide:25-54 added on Fri February 6 2015;propeptide:57-85 added on Fri February 6 2015;peptide:88-108 added on Fri February 6 2015
_displayName
UniProt:P01325 Ins1
_timestamp
2023-11-03 17:25:07
chain
signal peptide:1-24 peptide:25-54 propeptide:57-85 peptide:88-108
checksum
F63D9B7B896E0F88
comment
FUNCTION Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.SUBUNIT Heterodimer of a B chain and an A chain linked by two disulfide bonds.SUBCELLULAR LOCATION Belongs to the insulin family.
recommendedName: Insulin-1 component recommendedName: Insulin-1 B chain /component component recommendedName: Insulin-1 A chain /component
geneName
Ins1 Ins-1
identifier
P01325
isSequenceChanged
FALSE
keyword
3D-structure Carbohydrate metabolism Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Glucose metabolism Hormone Reference proteome Secreted Signal
