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Details on Person RASA1 [cytosol]

Class:Id	EntityWithAccessionedSequence:186833
_displayName	RASA1 [cytosol]
_timestamp	2013-08-14 14:52:57
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:186838] Jassal, B, 2006-08-24 13:02:57
endCoordinate	1047
modified	[InstanceEdit:3132750] Wu, G, 2013-02-13 [InstanceEdit:3632907] Wu, G, 2013-05-28 [InstanceEdit:4093311] Garapati, P V, 2013-08-14
name	RASA1 Ras GTPase-activating protein 1 p120-RasGAP
referenceEntity	[ReferenceGeneProduct:63760] UniProt:P20936 RASA1 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:399052] R-HSA-186833.1
startCoordinate	1
(activeUnit)	[CatalystActivity:208926] GTPase activator activity of RASA1:Ras:GTP [cytosol] [CatalystActivity:4093338] GTPase activator activity of p-EPHBs:EFNBs:RASA1:HRAS:GTP [plasma membrane] [CatalystActivity:8981352] GTPase activity of p21 RAS:GTP:RASA1 [plasma membrane]
(hasComponent)	[Complex:186830] Phospho-beta receptor homodimer:GAP [plasma membrane] [Homo sapiens] [Complex:206651] RASA1:Ras:GDP [cytosol] [Homo sapiens] [Complex:206801] RASA1:Ras:GTP [cytosol] [Homo sapiens] [Complex:4093322] p-EPHBs:EFNBs:RASA1 [plasma membrane] [Homo sapiens] [Complex:5218802] RASA1:p21 RAS:GTP:SPG [plasma membrane] [Homo sapiens] [Complex:8849093] p-Y1105-ARHGAP35:RASA1 [cytosol] [Homo sapiens] [Complex:8981350] p21 RAS:GTP:RASA1 [plasma membrane] [Homo sapiens]
(hasMember)	[DefinedSet:5658216] RAS GAPs [cytosol] [Homo sapiens]
(input)	[Reaction:186798] GAP binds to PDGF-beta receptors only [Homo sapiens] [Reaction:209208] Human RASA1 binds to Ras:GTP complex [Homo sapiens] [Reaction:4093330] EPHB binds p120-RasGAP [Homo sapiens] [Reaction:8849094] ARHGAP35 binds RASA1 [Homo sapiens] [Reaction:8981355] RASA1 binds RAS:GTP [Homo sapiens]
(output)	[Reaction:209288] Human RASA1 dissociates from Ras:GDP complex [Homo sapiens] [Reaction:5218845] p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate [Homo sapiens] [Reaction:8981353] RASA1 stimulates RAS GTPase activity [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9876805] Update Tracker - [EntityWithAccessionedSequence:186833] RASA1 [cytosol] - v44:[addEndCoordinate, addStartCoordinate] [_UpdateTracker:9888079] Update Tracker - [EntityWithAccessionedSequence:186833] RASA1 [cytosol] - v46:[modifyName]
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No pathways have been reviewed or authored by RASA1 [cytosol] (186833)