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Details on Person PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane]

Class:Id	Complex:186789
_displayName	PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane]
_timestamp	2017-09-22 09:46:08
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:186802] Jassal, B, 2006-08-15 13:51:10
hasComponent	[Complex:74693] PI3K [cytosol] [Homo sapiens] [DefinedSet:74688] PI3K-regulatory subunit [cytosol] [Homo sapiens] [DefinedSet:74689] PI3K-catalytic subunit [cytosol] [Homo sapiens] [Complex:186811] PDGF:Phospho-PDGF receptor dimer [plasma membrane] [Homo sapiens] [DefinedSet:186821] Phospho- PDGF receptor dimer [plasma membrane] [Homo sapiens] [DefinedSet:380760] Active PDGF dimers (AA, AB, BB) [extracellular region] [Homo sapiens]
modified	[InstanceEdit:380764] Garapati, P V, 2008-11-14 10:45:10 [InstanceEdit:9022235] Jassal, Bijay, 2017-09-22
name	PDGF:Phospho-PDGF receptor dimer:PI3K
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:399254] R-HSA-186789.2
(hasMember)	[DefinedSet:2316432] Activator:PI3K [plasma membrane] [Homo sapiens]
(normalEntity)	[EntityFunctionalStatus:9672144] gain_of_function of p-11Y PDGFR mutant dimers:PI3K [plasma membrane]
(output)	[Reaction:186780] PI3-kinase binds to the active receptor [Homo sapiens]
(physicalEntity)	[CatalystActivity:186820] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane]
(updatedInstance)	[_UpdateTracker:9868843] Update Tracker - [Complex:186789] PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] - v32:[updateContainedComponent] [_UpdateTracker:9894576] Update Tracker - [Complex:186789] PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] - v57:[updateContainedComponent] [_UpdateTracker:9897929] Update Tracker - [Complex:186789] PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] - v63:[add_removeHasComponent]
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No pathways have been reviewed or authored by PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (186789)