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Details on Person Autophosphorylation of PDGF beta receptors

Class:IdReaction:186786
_displayNameAutophosphorylation of PDGF beta receptors
_doReleaseTRUE
_timestamp2010-01-25 11:02:25
authored[InstanceEdit:382627] Garapati, P V, Jassal, B, 2008-11-24 10:14:27
catalystActivity[CatalystActivity:469653] protein tyrosine kinase activity of PDGF beta receptor:PDGF chain B homodimer [plasma membrane]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:186802] Jassal, B, 2006-08-15 13:51:10
edited[InstanceEdit:382627] Garapati, P V, Jassal, B, 2008-11-24 10:14:27
input[Complex:389078] PDGF beta receptor:PDGF chain B homodimer [plasma membrane] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
literatureReference[LiteratureReference:380735] Signal transduction via platelet-derived growth factor receptors
modified[InstanceEdit:382619] Garapati, P V, 2008-11-24 00:29:42
[InstanceEdit:382628] Garapati, P V, 2008-11-24 10:23:08
[InstanceEdit:389087] Garapati, P V, 2008-12-19 10:29:26
[InstanceEdit:392248] Garapati, P V, 2009-03-01 16:05:31
[InstanceEdit:469650] Garapati, P V, 2010-01-25
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameAutophosphorylation of PDGF beta receptors
output[Complex:389074] Phospho PDGF beta receptor: PDGF chain B homodimer [plasma membrane] [Homo sapiens]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
precedingEvent
releaseDate2009-04-01
reviewed[InstanceEdit:382617] Heldin, CH, 2008-11-23 19:29:34
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:398355] R-HSA-186786.2
summation[Summation:186790] Receptor dimerisation is key event in PDGF receptor activati...
(hasEvent)[Pathway:186797] Signaling by PDGF [Homo sapiens]
(precedingEvent)[Reaction:186765] PLC-gamma binds to the active receptor [Homo sapiens]
[Reaction:186778] SHP2 binds to the active receptor [Homo sapiens]
[Reaction:186780] PI3-kinase binds to the active receptor [Homo sapiens]
[Reaction:186798] GAP binds to PDGF-beta receptors only [Homo sapiens]
[Reaction:186819] SH2 domain of Src binds to the active receptor [Homo sapiens]
[Reaction:186826] GRB2:SOS1 complex binds to the active receptor [Homo sapiens]
[Reaction:380782] STAT binds to the active receptor [Homo sapiens]
[Reaction:382055] Grb7 binds to the active PDGF receptor [Homo sapiens]
[Reaction:382056] Crk binds to the active PDGF receptor [Homo sapiens]
[Reaction:382058] Nck binds to the active PDGF receptor [Homo sapiens]
List all 11 refering instances
(updatedInstance)[_UpdateTracker:9777081] Update Tracker - [Reaction:186786] Autophosphorylation of PDGF beta receptors - v72:[modifyText]
[_UpdateTracker:9790848] Update Tracker - [Reaction:186786] Autophosphorylation of PDGF beta receptors - v32:[add_removeCatalystActivity]
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