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Details on Person Phosphatidylinositol 3'-kinases (PI3Ks) are a family of enzy...

Class:Id	Summation:186784
_displayName	Phosphatidylinositol 3'-kinases (PI3Ks) are a family of enzy...
_timestamp	2020-02-08 16:56:53
created	[InstanceEdit:186802] Jassal, B, 2006-08-15 13:51:10
literatureReference	[LiteratureReference:381866] Role of phosphatidylinositol kinase in PDGF receptor signal transduction [LiteratureReference:380735] Signal transduction via platelet-derived growth factor receptors
modified	[InstanceEdit:186838] Jassal, B, 2006-08-24 13:02:57 [InstanceEdit:381876] Garapati, P V, 2008-11-21 17:55:36 [InstanceEdit:382622] Garapati, P V, 2008-11-24 00:32:38 [InstanceEdit:9674505] Rothfels, Karen, 2020-01-13 [InstanceEdit:9676121] Rothfels, Karen, 2020-02-08
text	Phosphatidylinositol 3'-kinases (PI3Ks) are a family of enzymes which can phosphorylate phosphoinositides. PI3Ks bind to and are activated by PDGF receptors. Tyr 740 and Tyr 751 in PDGF beta-receptor, and Tyr 731 and Tyr 742 in PDGF alpha-receptor have been shown to be autophosphorylation sites and to bind PI3-kinase.
(summation)	[Reaction:186780] PI3-kinase binds to the active receptor [Homo sapiens]
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