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Details on Person PDX1 transactivates Iapp

Class:IdBlackBoxEvent:186609
_displayNamePDX1 transactivates Iapp
_doReleaseTRUE
_timestamp2012-11-25 19:21:02
authored[InstanceEdit:351500] Ferrer, J, Tello-Ruiz, MK, 2008-05-23
compartment[Compartment:7660] nucleoplasm
[Compartment:70101] cytosol
created[InstanceEdit:186665] Tello-Ruiz, MK, 2006-08-14 15:25:20
edited[InstanceEdit:190295] Tello-Ruiz, MK, 2006-12-19 19:02:30
literatureReference[LiteratureReference:186720] Quantitative assessment of gene targeting in vitro and in vivo by the pancreatic transcription factor, Pdx1. Importance of chromatin structure in directing promoter binding.
[LiteratureReference:186519] beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes
modified[InstanceEdit:187098] Tello-Ruiz, MK, 2006-09-08 18:39:34
[InstanceEdit:187191] Tello-Ruiz, MK, 2006-09-08 22:11:04
[InstanceEdit:187248] Tello-Ruiz, MK, 2006-09-11 23:46:47
[InstanceEdit:187302] Tello-Ruiz, MK, 2006-09-13 01:14:23
[InstanceEdit:189125] Tello-Ruiz, MK, 2006-11-03 15:56:51
[InstanceEdit:189535] Tello-Ruiz, MK, 2006-11-27 21:00:31
[InstanceEdit:189794] Tello-Ruiz, MK, 2006-12-01 23:20:56
[InstanceEdit:189795] Tello-Ruiz, MK, 2006-12-01 23:55:51
[InstanceEdit:190279] Tello-Ruiz, MK, 2006-12-18 20:27:37
[InstanceEdit:190281] Tello-Ruiz, MK, 2006-12-18 20:36:22
[InstanceEdit:194433] Schmidt, EE, 2007-03-13 12:36:50
[InstanceEdit:210754] D'Eustachio, P, 2008-01-15 23:30:08
[InstanceEdit:349416] D'Eustachio, P, 2008-05-07 20:42:40
[InstanceEdit:349684] D'Eustachio, P, 2008-05-12 21:51:33
[InstanceEdit:350214] D'Eustachio, P, 2008-05-14 17:51:53
[InstanceEdit:351498] D'Eustachio, P, 2008-05-23 22:55:12
[InstanceEdit:2671770] D'Eustachio, P, 2012-11-25
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePDX1 transactivates Iapp
output[EntityWithAccessionedSequence:189740] iapp [cytosol] [Mus musculus]
regulatedBy[PositiveRegulation:189787] Positive regulation by 'ipf1/pdx1 [nucleoplasm]'
releaseDate2008-06-30
reviewed[InstanceEdit:349683] Jensen, J, 2008-05-12 21:46:53
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48892] Mus musculus
stableIdentifier[StableIdentifier:360400] R-MMU-186609.3
summation[Summation:186687] Binding of Pdx1 to the 5'-flanking region of the IAPP gene w...
(inferredFrom)[BlackBoxEvent:211301] PDX1-dependent synthesis of IAPP protein [Homo sapiens]
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