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Details on Person PDX1 transactivates Iapp
Class:Id BlackBoxEvent:186609
_displayName PDX1 transactivates Iapp
_doRelease TRUE
_timestamp 2012-11-25 19:21:02
authored [InstanceEdit:351500] Ferrer, J, Tello-Ruiz, MK, 2008-05-23
compartment [Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created [InstanceEdit:186665] Tello-Ruiz, MK, 2006-08-14 15:25:20
edited [InstanceEdit:190295] Tello-Ruiz, MK, 2006-12-19 19:02:30
literatureReference [LiteratureReference:186720] Quantitative assessment of gene targeting in vitro and in vivo by the pancreatic transcription factor, Pdx1. Importance of chromatin structure in directing promoter binding. [LiteratureReference:186519] beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes
modified [InstanceEdit:187098] Tello-Ruiz, MK, 2006-09-08 18:39:34 [InstanceEdit:187191] Tello-Ruiz, MK, 2006-09-08 22:11:04 [InstanceEdit:187248] Tello-Ruiz, MK, 2006-09-11 23:46:47 [InstanceEdit:187302] Tello-Ruiz, MK, 2006-09-13 01:14:23 [InstanceEdit:189125] Tello-Ruiz, MK, 2006-11-03 15:56:51 [InstanceEdit:189535] Tello-Ruiz, MK, 2006-11-27 21:00:31 [InstanceEdit:189794] Tello-Ruiz, MK, 2006-12-01 23:20:56 [InstanceEdit:189795] Tello-Ruiz, MK, 2006-12-01 23:55:51 [InstanceEdit:190279] Tello-Ruiz, MK, 2006-12-18 20:27:37 [InstanceEdit:190281] Tello-Ruiz, MK, 2006-12-18 20:36:22 [InstanceEdit:194433] Schmidt, EE, 2007-03-13 12:36:50 [InstanceEdit:210754] D'Eustachio, P, 2008-01-15 23:30:08 [InstanceEdit:349416] D'Eustachio, P, 2008-05-07 20:42:40 [InstanceEdit:349684] D'Eustachio, P, 2008-05-12 21:51:33 [InstanceEdit:350214] D'Eustachio, P, 2008-05-14 17:51:53 [InstanceEdit:351498] D'Eustachio, P, 2008-05-23 22:55:12 [InstanceEdit:2671770] D'Eustachio, P, 2012-11-25 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name PDX1 transactivates Iapp
output [EntityWithAccessionedSequence:189740] iapp [cytosol] [Mus musculus]
regulatedBy [PositiveRegulation:189787] Positive regulation by 'ipf1/pdx1 [nucleoplasm]'
releaseDate 2008-06-30
reviewed [InstanceEdit:349683] Jensen, J, 2008-05-12 21:46:53
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48892] Mus musculus
stableIdentifier [StableIdentifier:360400] R-MMU-186609.3
summation [Summation:186687] Binding of Pdx1 to the 5'-flanking region of the IAPP gene w...
(inferredFrom) [BlackBoxEvent:211301] PDX1-dependent synthesis of IAPP protein [Homo sapiens]
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