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Details on Person PI3K binds to p-6Y-SYK

Class:Id	Reaction:1861731
_displayName	PI3K binds to p-6Y-SYK
_timestamp	2016-07-15 23:48:56
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:1861649] Garapati, P V, 2011-10-31
input	[Complex:74693] PI3K [cytosol] [Homo sapiens] [Complex:1861618] clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:1861717] Molecular basis for a direct interaction between the Syk protein-tyrosine kinase and phosphoinositide 3-kinase [LiteratureReference:1861563] Class I phosphoinositide 3-kinase p110beta is required for apoptotic cell and Fcgamma receptor-mediated phagocytosis by macrophages
modified	[InstanceEdit:8879177] Wu, G, 2016-07-15
name	PI3K binds to p-6Y-SYK
output	[Complex:1861580] PI3K:p-6Y-SYK [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:1861629] Phosphorylation of SYK by Src kinases [Homo sapiens] [Reaction:1861586] Recruitment of SYK to phosphorylated ITAMs [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8880480] R-HSA-1861731.1
summation	[Summation:1861632] PI3K is one of the downstream effector of activated SYK. The...
(precedingEvent)	[Reaction:1861631] PI3K phosphorylates PIP2 to PIP3 [Homo sapiens]
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No pathways have been reviewed or authored by PI3K binds to p-6Y-SYK (1861731)