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Details on Person PI3K phosphorylates PIP2 to PIP3

Class:IdReaction:1861631
_displayNamePI3K phosphorylates PIP2 to PIP3
_doReleaseFALSE
_timestamp2016-07-15 23:49:23
catalystActivity[CatalystActivity:1861701] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of PI3K:p-6Y-SYK [plasma membrane]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:1861649] Garapati, P V, 2011-10-31
input[SimpleEntity:179856] PI(4,5)P2 [plasma membrane]
[SimpleEntity:113592] ATP [cytosol]
literatureReference[LiteratureReference:1861673] Restricted accumulation of phosphatidylinositol 3-kinase products in a plasmalemmal subdomain during Fc gamma receptor-mediated phagocytosis
[LiteratureReference:202402] The role of PI3K in immune cells
[LiteratureReference:1861728] Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis
modified[InstanceEdit:8879177] Wu, G, 2016-07-15
namePI3K phosphorylates PIP2 to PIP3
output[SimpleEntity:179838] PI(3,4,5)P3 [plasma membrane]
[SimpleEntity:29370] ADP [cytosol]
precedingEvent
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8893701] R-HSA-1861631.1
summation[Summation:1861678] Activated PI3K phosphorylates phosphatidylinositol (PI) 4-ph...
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No pathways have been reviewed or authored by PI3K phosphorylates PIP2 to PIP3 (1861631)
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