Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Recruitment of SYK to phosphorylated ITAMs

Class:Id	Reaction:1861586
_displayName	Recruitment of SYK to phosphorylated ITAMs
_timestamp	2016-07-15 23:50:13
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region [Compartment:70101] cytosol
created	[InstanceEdit:1861649] Garapati, P V, 2011-10-31
input	[Complex:1861662] clustered IgG-Ag:p-FCGRs [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:58268] SYK [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:1861556] A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages [LiteratureReference:1861620] Cross-linking of Fc gamma receptor I (Fc gamma RI) and receptor II (Fc gamma RII) on monocytic cells activates a signal transduction pathway common to both Fc receptors that involves the stimulation of p72 Syk protein tyrosine kinase [LiteratureReference:1861684] Involvement of p72syk, a protein-tyrosine kinase, in Fc gamma receptor signaling [LiteratureReference:1861737] Protein-tyrosine kinase p72syk in Fc gamma RI receptor signaling [LiteratureReference:1861604] Tyrosine phosphorylation and association of Syk with Fc gamma RII in monocytic THP-1 cells [LiteratureReference:1861686] Abrogation of the Fc gamma receptor IIA-mediated phagocytic signal by stem-loop Syk antisense oligonucleotides [LiteratureReference:453188] Molecular mechanism of the Syk activation switch
modified	[InstanceEdit:8879177] Wu, G, 2016-07-15
name	Recruitment of SYK to phosphorylated ITAMs
output	[Complex:1861554] clustered IgG-Ag:p-FCGRs:SYK [plasma membrane] [Homo sapiens]
precedingEvent	[BlackBoxEvent:1861587] Sequestring and phosphorylation Fc gamma receptors in the lipid rafts [Homo sapiens] [Reaction:1861680] Cross-linking of FCGRIA with IgG-coated Ag [Homo sapiens] [Reaction:1861725] Cross-linking of FCGRIIIA with IgG-coated Ag [Homo sapiens] [Reaction:1861621] Cross-linking of FCGRIIA with IgG-coated Ag [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8914737] R-HSA-1861586.1
summation	[Summation:1861740] SYK is a tyrosine kinase related to ZAP70 that is expressed ...
(precedingEvent)	[Reaction:1861629] Phosphorylation of SYK by Src kinases [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by Recruitment of SYK to phosphorylated ITAMs (1861586)