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Details on Person I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus

Class:IdReaction:1855228
_displayNameI(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus
_doReleaseTRUE
_timestamp2025-09-23 15:50:47
authored[InstanceEdit:1855226] Williams, MG, 2011-10-28
catalystActivity[CatalystActivity:2023903] inositol-1,3,4,6-tetrakisphosphate 5-kinase activity of IPMK [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:1855226] Williams, MG, 2011-10-28
crossReference[DatabaseIdentifier:9966587] RHEA:12718
edited[InstanceEdit:1855226] Williams, MG, 2011-10-28
input[SimpleEntity:2023892] I(1,3,4,6)P4 [nucleoplasm]
[SimpleEntity:29358] ATP [nucleoplasm]
isChimericFALSE
literatureReference[LiteratureReference:1889896] The human homolog of the rat inositol phosphate multikinase is an inositol 1,3,4,6-tetrakisphosphate 5-kinase
[LiteratureReference:1889765] Inositol polyphosphate multikinase regulates inositol 1,4,5,6-tetrakisphosphate
modified[InstanceEdit:1884039] Williams, MG, 2011-10-31
[InstanceEdit:1889946] Williams, MG, 2011-11-01
[InstanceEdit:2023905] Williams, MG, 2011-12-13
[InstanceEdit:2562613] D'Eustachio, P, 2012-11-06
[InstanceEdit:2565867] D'Eustachio, P, 2012-11-08
[InstanceEdit:2566982] D'Eustachio, P, 2012-11-09
[InstanceEdit:2836586] D'Eustachio, P, 2012-12-11
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9966590] Stephan, Ralf, 2025-09-22
[InstanceEdit:9966626] D'Eustachio, Peter, 2025-09-23
nameI(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus
output[SimpleEntity:2023901] I(1,3,4,5,6)P5 [nucleoplasm]
[SimpleEntity:113582] ADP [nucleoplasm]
[SimpleEntity:9668967] H+ [nucleoplasm]
precedingEvent
previousReviewStatus[ReviewStatus:9821384] two stars
releaseDate2012-12-04
reviewed[InstanceEdit:2562610] Wundenberg, Torsten, 2012-11-06
[InstanceEdit:9966625] D'Eustachio, Peter, 2025-09-23
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:3200355] R-HSA-1855228.4
structureModified[InstanceEdit:9966590] Stephan, Ralf, 2025-09-22
summation[Summation:2023902] In the nucleus, inositol polyphosphate multikinase (IPMK) ph...
(hasEvent)[Pathway:1855191] Synthesis of IPs in the nucleus [Homo sapiens]
(precedingEvent)[Reaction:1855161] I(1,3,4,5,6)P5 transports from the nucleus to the cytosol [Homo sapiens]
[Reaction:1855176] I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus [Homo sapiens]
[Reaction:1855181] I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus [Homo sapiens]
(updatedInstance)[_UpdateTracker:9971892] Update Tracker - [Reaction:1855228] I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus - v95:[removeOutput]
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No pathways have been reviewed or authored by I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (1855228)