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Details on Person IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol

Class:IdReaction:1855227
_displayNameIP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol
_doReleaseTRUE
_timestamp2016-11-10 00:55:38
authored[InstanceEdit:1855226] Williams, MG, 2011-10-28
catalystActivity[CatalystActivity:2023958] inositol hexakisphosphate kinase activity of IP6K1/3 [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:1855226] Williams, MG, 2011-10-28
edited[InstanceEdit:1855226] Williams, MG, 2011-10-28
input[SimpleEntity:1629770] IP6 [cytosol]
[SimpleEntity:113592] ATP [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:1889803] Identification and characterization of a novel inositol hexakisphosphate kinase
[LiteratureReference:1889868] A conserved family of enzymes that phosphorylate inositol hexakisphosphate
[LiteratureReference:1889876] Inositol hexakisphosphate kinase products contain diphosphate and triphosphate groups
[LiteratureReference:1889794] Structural analysis and detection of biological inositol pyrophosphates reveal that the family of VIP/diphosphoinositol pentakisphosphate kinases are 1/3-kinases
modified[InstanceEdit:1884039] Williams, MG, 2011-10-31
[InstanceEdit:1889946] Williams, MG, 2011-11-01
[InstanceEdit:2023980] Williams, MG, 2011-12-13
[InstanceEdit:2562613] D'Eustachio, P, 2012-11-06
[InstanceEdit:2564838] D'Eustachio, P, 2012-11-07
[InstanceEdit:2565867] D'Eustachio, P, 2012-11-08
[InstanceEdit:2566982] D'Eustachio, P, 2012-11-09
[InstanceEdit:2836586] D'Eustachio, P, 2012-12-11
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameIP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol
output[SimpleEntity:1629765] 5-PP-IP5 [cytosol]
[SimpleEntity:29370] ADP [cytosol]
precedingEvent
releaseDate2012-12-04
reviewed[InstanceEdit:2562610] Wundenberg, Torsten, 2012-11-06
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:3200300] R-HSA-1855227.3
summation[Summation:2023956] Inositol hexakisphosphate kinase 1 (IP6K1) and 3 (IP6K3) pho...
(hasEvent)[Pathway:1855167] Synthesis of pyrophosphates in the cytosol [Homo sapiens]
(precedingEvent)[Reaction:1855158] 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol [Homo sapiens]
[Reaction:1855182] 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol [Homo sapiens]
[Reaction:1855198] 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol [Homo sapiens]
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No pathways have been reviewed or authored by IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (1855227)
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