Query author contributions in Reactome Reactome depends on collaboration between our curation team and outside experts to
assemble and peer-review its pathway modules. The integration of ORCID within Reactome
enables us to meet a key challenge with authoring, curating and reviewing biological
information by incentivizing and crediting the external experts that contribute their
expertise and time to the Reactome curation process. More information is available at
ORCID and Reactome .
If you have an ORCID ID that is not listed on this page, please
forward this information to us and we will update your Reactome pathway records.
Details on Person 5-PP-IP4 transports from the nucleus to the cytosol
Class:Id Reaction:1855173
_displayName 5-PP-IP4 transports from the nucleus to the cytosol
_doRelease TRUE
_timestamp 2025-12-16 21:52:40
authored [InstanceEdit:1855226] Williams, MG, 2011-10-28
catalystActivity [CatalystActivity:9954155] narrow pore channel activity of Nuclear Pore Complex (NPC) [nuclear envelope]
compartment [Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created [InstanceEdit:1855226] Williams, MG, 2011-10-28
edited [InstanceEdit:1855226] Williams, MG, 2011-10-28
goBiologicalProcess [GO_BiologicalProcess:160102] nuclear export
input [SimpleEntity:2023922] 5-PP-IP4 [nucleoplasm]
internalReviewed [InstanceEdit:9968056] D'Eustachio, Peter, 2025-10-08 [InstanceEdit:9977081] D'Eustachio, Peter, 2025-12-16
isChimeric FALSE
literatureReference [LiteratureReference:1889803] Identification and characterization of a novel inositol hexakisphosphate kinase [LiteratureReference:1889872] The inositol hexakisphosphate kinase family. Catalytic flexibility and function in yeast vacuole biogenesis
modified [InstanceEdit:1884039] Williams, MG, 2011-10-31 [InstanceEdit:1889946] Williams, MG, 2011-11-01 [InstanceEdit:2023938] Williams, MG, 2011-12-13 [InstanceEdit:2562613] D'Eustachio, P, 2012-11-06 [InstanceEdit:2565867] D'Eustachio, P, 2012-11-08 [InstanceEdit:2566982] D'Eustachio, P, 2012-11-09 [InstanceEdit:2836586] D'Eustachio, P, 2012-12-11 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9954157] D'Eustachio, Peter, 2025-06-06 [InstanceEdit:9954161] D'Eustachio, Peter, 2025-06-06 [InstanceEdit:9963234] D'Eustachio, Peter, 2025-08-13 [InstanceEdit:9968055] D'Eustachio, Peter, 2025-10-08 [InstanceEdit:9968057] D'Eustachio, Peter, 2025-10-08 [InstanceEdit:9968060] D'Eustachio, Peter, 2025-10-08 [InstanceEdit:9977080] D'Eustachio, Peter, 2025-12-16 [InstanceEdit:9977082] D'Eustachio, Peter, 2025-12-16 [InstanceEdit:9977085] D'Eustachio, Peter, 2025-12-16
name 5-PP-IP4 transports from the nucleus to the cytosol
output [SimpleEntity:1629755] 5-PP-IP4 [cytosol]
precedingEvent [Reaction:1855181] I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus [Homo sapiens]
[BlackBoxEvent:1855160] I(1,3,4,5,6)P5 transports from the ER lumen to the nucleus [Homo sapiens]
[Reaction:1855206] I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus [Homo sapiens]
[Reaction:1855228] I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus [Homo sapiens]
[Reaction:1855185] I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus [Homo sapiens]
previousReviewStatus [ReviewStatus:9821385] four stars
releaseDate 2012-12-04
reviewed [InstanceEdit:2562610] Wundenberg, Torsten, 2012-11-06 [InstanceEdit:9968059] Hill, David P, 2025-10-08 [InstanceEdit:9977084] Hill, David P, 2025-12-16
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:3200370] R-HSA-1855173.6
structureModified [InstanceEdit:9954157] D'Eustachio, Peter, 2025-06-06 [InstanceEdit:9968055] D'Eustachio, Peter, 2025-10-08 [InstanceEdit:9977080] D'Eustachio, Peter, 2025-12-16
summation [Summation:2023917] Inositol 5-diphospho-1,3,4,6-tetrakisphosphate (5-PP-IP4) tr...
(hasEvent) [Pathway:1855170] IPs transport between nucleus and cytosol [Homo sapiens]
(precedingEvent) [Reaction:1855166] PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol [Homo sapiens] [Reaction:1855193] 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol [Homo sapiens]
(updatedInstance) [_UpdateTracker:9964622] Update Tracker - [Reaction:1855173] 5-PP-IP4 transports from the nucleus to the cytosol - v94:[removeCatalystActivity] [_UpdateTracker:9971791] Update Tracker - [Reaction:1855173] 5-PP-IP4 transports from the nucleus to the cytosol - v95:[addCatalystActivity, modifyText] [_UpdateTracker:9984591] Update Tracker - [Reaction:1855173] 5-PP-IP4 transports from the nucleus to the cytosol - v96:[removeCatalystActivity]
[Change default viewing format]
List...
Protein identifiers
ChEBI identifiers
KEGG COMPOUND identifiers
No pathways have been reviewed or authored by 5-PP-IP4 transports from the nucleus to the cytosol (1855173)