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Details on Person I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol

Class:Id	Reaction:1855162
_displayName	I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol
_doRelease	TRUE
_timestamp	2016-11-10 00:56:15
authored	[InstanceEdit:1855226] Williams, MG, 2011-10-28
catalystActivity	[CatalystActivity:2023985] inositol-3,4,5,6-tetrakisphosphate 1-kinase activity of ITPK1:Mg2+ [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1855226] Williams, MG, 2011-10-28
edited	[InstanceEdit:1855226] Williams, MG, 2011-10-28
input	[SimpleEntity:994149] I(3,4,5,6)P4 [cytosol] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:994172] Multitasking in signal transduction by a promiscuous human Ins(3,4,5,6)P(4) 1-kinase/Ins(1,3,4)P(3) 5/6-kinase
modified	[InstanceEdit:1884039] Williams, MG, 2011-10-31 [InstanceEdit:1889946] Williams, MG, 2011-11-01 [InstanceEdit:2023980] Williams, MG, 2011-12-13 [InstanceEdit:2562613] D'Eustachio, P, 2012-11-06 [InstanceEdit:2564838] D'Eustachio, P, 2012-11-07 [InstanceEdit:2565867] D'Eustachio, P, 2012-11-08 [InstanceEdit:2566982] D'Eustachio, P, 2012-11-09 [InstanceEdit:2836586] D'Eustachio, P, 2012-12-11 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol
output	[SimpleEntity:994141] I(1,3,4,5,6)P5 [cytosol] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:1855219] I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol [Homo sapiens] [Reaction:1855161] I(1,3,4,5,6)P5 transports from the nucleus to the cytosol [Homo sapiens] [Reaction:1855162] I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol [Homo sapiens] [Reaction:1855166] PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol [Homo sapiens] [Reaction:1855155] I(1,3,4,5,6)P5 transports from the ER lumen to the cytosol [Homo sapiens]
releaseDate	2012-12-04
reviewed	[InstanceEdit:2562610] Wundenberg, Torsten, 2012-11-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:3200343] R-HSA-1855162.3
summation	[Summation:2023960] Inositoltetrakisphosphate 1-kinase (ITPK1) phosphorylates in...
(hasEvent)	[Pathway:1855167] Synthesis of pyrophosphates in the cytosol [Homo sapiens]
(precedingEvent)	[Reaction:1855179] I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol [Homo sapiens] [Reaction:1855195] I(1,3,4,5,6)P5 transports from the cytosol to the ER lumen [Homo sapiens] [Reaction:1855219] I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol [Homo sapiens] [Reaction:1855223] I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol [Homo sapiens] [Reaction:9687638] MLKL binds IP4, IP5 and IP6 [Homo sapiens]
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No pathways have been reviewed or authored by I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (1855162)