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Details on Person I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol

Class:Id	Reaction:1855154
_displayName	I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol
_doRelease	TRUE
_timestamp	2025-09-22 08:50:23
authored	[InstanceEdit:1855226] Williams, MG, 2011-10-28
catalystActivity	[CatalystActivity:2024043] inositol monophosphate 1-phosphatase activity of IMPA1/2 [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1855226] Williams, MG, 2011-10-28
crossReference	[DatabaseIdentifier:9966610] RHEA:27671
edited	[InstanceEdit:1855226] Williams, MG, 2011-10-28
input	[SimpleEntity:870330] I1P [cytosol] [SimpleEntity:29356] H2O [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:1889889] cDNA cloning of human and rat brain myo-inositol monophosphatase. Expression and characterization of the human recombinant enzyme [LiteratureReference:1889781] Spatial expression patterns and biochemical properties distinguish a second myo-inositol monophosphatase IMPA2 from IMPA1
modified	[InstanceEdit:1889946] Williams, MG, 2011-11-01 [InstanceEdit:1914818] Williams, MG, 2011-11-02 [InstanceEdit:2024022] Williams, MG, 2011-12-13 [InstanceEdit:2562613] D'Eustachio, P, 2012-11-06 [InstanceEdit:2564838] D'Eustachio, P, 2012-11-07 [InstanceEdit:2565867] D'Eustachio, P, 2012-11-08 [InstanceEdit:2566982] D'Eustachio, P, 2012-11-09 [InstanceEdit:2836586] D'Eustachio, P, 2012-12-11 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9966597] Stephan, Ralf, 2025-09-22
name	I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol
output	[SimpleEntity:426910] Ins [cytosol] [SimpleEntity:29372] Pi [cytosol]
releaseDate	2012-12-04
reviewed	[InstanceEdit:2562610] Wundenberg, Torsten, 2012-11-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:3200373] R-HSA-1855154.4
summation	[Summation:2024027] Inositol monophosphatase 1 (IMPA1) and 2 (IMPA2) homodimers ...
(hasEvent)	[Pathway:1855183] Synthesis of IP2, IP, and Ins in the cytosol [Homo sapiens]
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