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Details on Person C3(H2O):Factor Bb cleaves C3 to C3b and C3a

Class:Id	Reaction:183130
_displayName	C3(H2O):Factor Bb cleaves C3 to C3b and C3a
_doRelease	TRUE
_timestamp	2016-11-10 00:54:29
authored	[InstanceEdit:173743] de Bono, B, 2006-02-16 13:19:05
catalystActivity	[CatalystActivity:183125] serine-type endopeptidase activity of C3(H2O):Bb [extracellular region]
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:183129] de Bono, B, 2006-07-21 15:19:05
edited	[InstanceEdit:1022121] Jupe, S, 2010-11-17
input	[Complex:166822] Complement factor 3 [extracellular region] [Homo sapiens]
literatureReference	[LiteratureReference:173730] Molecular organization and function of the complement system
modified	[InstanceEdit:183132] de Bono, B, 2006-07-21 15:24:24 [InstanceEdit:981538] Jupe, S, 2010-10-22 [InstanceEdit:1022122] Jupe, S, 2010-11-17 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	C3(H2O):Factor Bb cleaves C3 to C3b and C3a
output	[EntityWithAccessionedSequence:166828] C3a [extracellular region] [Homo sapiens] [Complex:166832] C3b [extracellular region] [Homo sapiens]
precedingEvent	[Reaction:173745] Factor D cleaves C3(H2O)-bound Factor B [Homo sapiens] [Reaction:173740] Factor B binds to C3(H2O) [Homo sapiens]
releaseDate	2006-08-02
reviewed	[InstanceEdit:181939] D'Eustachio, P, 2006-07-03 21:35:13
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:358477] R-HSA-183130.3
summation	[Summation:183127] C3(H2O):Factor Bb is a C3 convertase, sometimes referred to ...
(hasEvent)	[Pathway:173736] Alternative complement activation [Homo sapiens]
(precedingEvent)	[Reaction:981539] C3b binds to cell surface [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9790139] Update Tracker - [Reaction:183130] C3(H2O):Factor Bb cleaves C3 to C3b and C3a - v35:[add_removeOutput, modifyText]
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No pathways have been reviewed or authored by C3(H2O):Factor Bb cleaves C3 to C3b and C3a (183130)