Query author contributions in Reactome
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Details on Person Factor D, a constitutively active serine protease found in t...
| Class:Id | Summation:183121 |
|---|---|
| _displayName | Factor D, a constitutively active serine protease found in t... |
| _timestamp | 2010-11-11 10:13:09 |
| created | [InstanceEdit:183129] de Bono, B, 2006-07-21 15:19:05 |
| literatureReference | [LiteratureReference:182527] Initiation of the alternative pathway of complement: recognition of activators by bound C3b and assembly of the entire pathway from six isolated proteins [LiteratureReference:182534] The alternative pathway C3/C5 convertase: chemical basis of factor B activation |
| modified | [InstanceEdit:981538] Jupe, S, 2010-10-22 [InstanceEdit:1011569] Jupe, S, 2010-11-11 |
| text | Factor D, a constitutively active serine protease found in trace amounts in the blood, cleaves a specific Arg-Lys bond in the Factor B component of the cell surface-associated C3b:Factor B complex, yielding the alternate C3 convertase C3bBb on the surface and releasing an inactive polypeptide, Factor Ba (Lesavre and Muller-Eberhard 1978; Lesavre et al. 1979; Schreiber et al. 1978). |
| (summation) | [Reaction:183122] Factor D cleaves C3b-bound Factor B [Homo sapiens] |
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No pathways have been reviewed or authored by Factor D, a constitutively active serine protease found in t... (183121)
