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Details on Person EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane]

Class:IdComplex:182953
_displayNameEGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane]
_timestamp2023-01-22 22:49:59
compartment[Compartment:876] plasma membrane
created[InstanceEdit:182919] Jassal, B, 2006-07-21 10:17:37
hasComponent
modified[InstanceEdit:1483239] Orlic-Milacic, Marija, 2011-08-12
[InstanceEdit:9031696] Orlic-Milacic, Marija, 2017-12-01
[InstanceEdit:9624455] Rothfels, Karen, 2018-10-11
[InstanceEdit:9824819] Orlic-Milacic, Marija, 2023-01-22
nameEGF-like ligands:p-6Y-EGFR:p-Y371-CBL
EGF:Phospho-EGFR (Y1069) dimer:Phospho-CBL
EGF:Phospho-EGFR (Y1045) dimer:Phospho-CBL
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:370162] R-HSA-182953.4
(hasComponent)[Complex:182961] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] [Homo sapiens]
(input)[Reaction:182993] Ubiquitination of stimulated EGFR (CBL) [Homo sapiens]
[Reaction:183072] EGFR non-clathrin mediated endocytosis [Homo sapiens]
[Reaction:183089] CBL binds and ubiquitinates phosphorylated Sprouty [Homo sapiens]
[Reaction:9846376] GOCAM Ubiquitination of stimulated EGFR (CBL) [Homo sapiens]
[Reaction:9846401] GOCAM CBL binds and ubiquitinates phosphorylated Sprouty [Homo sapiens]
[BlackBoxEvent:9846402] GOCAM EGFR non-clathrin mediated endocytosis [Homo sapiens]
(normalEntity)[EntityFunctionalStatus:5637714] loss_of_function of Ligand-responsive p-6Y-EGFR mutants:p-Y371-CBL [plasma membrane]
(output)[Reaction:182969] Phosphorylation of CBL (EGFR:CBL) [Homo sapiens]
[Reaction:9846381] GOCAM Phosphorylation of CBL (EGFR:CBL) [Homo sapiens]
(physicalEntity)[CatalystActivity:183074] ubiquitin-protein transferase activity of EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane]
(updatedInstance)[_UpdateTracker:9870349] Update Tracker - [Complex:182953] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] - v38:[addName, add_removeHasComponent]
[_UpdateTracker:9898500] Update Tracker - [Complex:182953] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] - v64:[add_removeHasComponent]
[_UpdateTracker:9899915] Update Tracker - [Complex:182953] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] - v67:[add_removeHasComponent, modifyName]
[_UpdateTracker:9904460] Update Tracker - [Complex:182953] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] - v84:[addName]
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No pathways have been reviewed or authored by EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] (182953)