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Details on Person EPS15 [cytosol]
Class:Id EntityWithAccessionedSequence:182920
_displayName EPS15 [cytosol]
_timestamp 2016-06-10 20:11:40
compartment [Compartment:70101] cytosol
created [InstanceEdit:182919] Jassal, B, 2006-07-21 10:17:37
endCoordinate 896
modified [InstanceEdit:3132750] Wu, G, 2013-02-13 [InstanceEdit:3632907] Wu, G, 2013-05-28 [InstanceEdit:8876264] Orlic-Milacic, Marija, 2016-06-10
name EPS15 Eps15
referenceEntity [ReferenceGeneProduct:54350] UniProt:P42566 EPS15 [Homo sapiens]
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:362647] R-HSA-182920.2
startCoordinate 1
(activeUnit) [CatalystActivity:9851543] protein-macromolecule adaptor activity of EPS15:HGS:STAM [cytosol]
(hasComponent) [Complex:182947] EPS15:HGS:STAM [cytosol] [Homo sapiens] [Complex:8856806] PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] [Homo sapiens] [Complex:8862276] PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] [Homo sapiens] [Complex:8868620] PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] [Homo sapiens] [Complex:8868624] PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] [Homo sapiens] [Complex:8868626] PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] [Homo sapiens] [Complex:8868627] PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] [Homo sapiens] [Complex:8868629] PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] [Homo sapiens] [Complex:8868632] PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] [Homo sapiens] [Complex:8868636] PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo:PIK3C2A [plasma membrane] [Homo sapiens]
(hasMember) [DefinedSet:8866243] EPS15,EPN1,EPN2 [cytosol] [Homo sapiens]
(input) [Reaction:8862280] FCHo proteins bind nascent clathrin-coated pit [Homo sapiens]
(output) [BlackBoxEvent:8869438] Dissociation of clathrin-associated proteins [Homo sapiens]
(regulator) [PositiveRegulation:9934674] Positive regulation by 'EPS15 [cytosol]'
(updatedInstance) [_UpdateTracker:9878638] Update Tracker - [EntityWithAccessionedSequence:182920] EPS15 [cytosol] - v44:[modifyEndCoordinate] [_UpdateTracker:9884989] Update Tracker - [EntityWithAccessionedSequence:182920] EPS15 [cytosol] - v45:[addName]
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Pathways
No pathways have been reviewed or authored by EPS15 [cytosol] (182920)