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Details on Person Formation of CD8:Nef:AP-2 Complex:v-ATPase Complex

Class:IdReaction:182186
_displayNameFormation of CD8:Nef:AP-2 Complex:v-ATPase Complex
_doReleaseTRUE
_timestamp2014-12-12 21:44:08
authored[InstanceEdit:200905] Gillespie, ME, 2007-07-25 19:42:36
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:182206] Gillespie, ME, 2006-07-06 19:48:37
disease[Disease:1660559] Human immunodeficiency virus infectious disease
input[EntityWithAccessionedSequence:167602] ATP6V1H [plasma membrane] [Homo sapiens]
[Complex:167712] AP-2 Complex [cytosol] [Homo sapiens]
[Complex:182194] CD8:Nef Complex [plasma membrane] [Homo sapiens]
literatureReference[LiteratureReference:182276] Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8alphabeta
modified[InstanceEdit:182300] Gillespie, ME, 2006-07-06 21:32:56
[InstanceEdit:182793] Gillespie, ME, 2006-07-18 19:30:59
[InstanceEdit:200904] Gillespie, ME, 2007-07-25 19:41:48
[InstanceEdit:200905] Gillespie, ME, 2007-07-25 19:42:36
[InstanceEdit:200907] Gillespie, ME, 2007-07-25 21:01:05
[InstanceEdit:201389] Gillespie, ME, 2007-08-07 14:42:02
[InstanceEdit:201413] Gopinathrao, G, 2007-08-08 14:30:28
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:5621512] Matthews, Lisa, 2014-08-29
[InstanceEdit:5656435] Gillespie, Marc E, 2014-12-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameFormation of CD8:Nef:AP-2 Complex:v-ATPase Complex
output[Complex:182158] CD8:Nef:AP-2 Complex:v-ATPase Complex [plasma membrane] [Homo sapiens]
relatedSpecies[Species:164493] Human immunodeficiency virus 1
releaseDate2007-08-21
reviewed[InstanceEdit:201388] Skowronski, J, 2007-08-07 14:33:41
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359334] R-HSA-182186.2
summation[Summation:200875] The presence of Nef accelerates endocytosis and lysosomal de...
(hasEvent)[Pathway:182218] Nef Mediated CD8 Down-regulation [Homo sapiens]
(precedingEvent)[Reaction:182198] Internalization of the CD8:Nef:AP-2 Complex:v-ATPase Complex [Homo sapiens]
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