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Details on Person Regulated secretion of neurotrophins by metabotropic glutamate group I (mGluRI) and Trk receptor activation is mediated via phospholipase C signalling pathways

Class:IdLiteratureReference:182046
_displayNameRegulated secretion of neurotrophins by metabotropic glutamate group I (mGluRI) and Trk receptor activation is mediated via phospholipase C signalling pathways
_timestamp2006-07-06 08:16:18
author[Person:182009] Canossa, M
[Person:182082] Gartner, A
[Person:182070] Campana, G
[Person:182059] Inagaki, N
[Person:182019] Thoenen, H
created[InstanceEdit:182105] Jassal, Bijay, 2006-07-06
journalEMBO J
pages1640-50
pubMedIdentifier11285228
titleRegulated secretion of neurotrophins by metabotropic glutamate group I (mGluRI) and Trk receptor activation is mediated via phospholipase C signalling pathways
volume20
year2001
(literatureReference)[Reaction:182040] Binding of Plcg1 to active Trk receptor [Rattus norvegicus]
[Reaction:182052] IP3 binds to the IP3 receptor, opening the Ca2+ channel [Rattus norvegicus]
[Reaction:182061] Active Plcg1 hydrolyses PIP2 [Rattus norvegicus]
[Reaction:182072] Active Trk phosphorylates Plcg1 [Rattus norvegicus]
[Reaction:182091] Active Plcg1 dissociates from Trk receptor [Rattus norvegicus]
[Reaction:182097] Calcium release from intracellular stores by IP3 receptor activation [Rattus norvegicus]
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