Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Trk receptor autophosphorylates

Class:IdReaction:181812
_displayNameTrk receptor autophosphorylates
_doReleaseTRUE
_timestamp2016-11-10 00:57:18
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:181805] Jassal, Bijay, 2006-06-20
input[Complex:181785] NGF dimer:Trk receptor dimer [plasma membrane] [Rattus norvegicus]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
literatureReference[LiteratureReference:181801] Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses
[LiteratureReference:181809] Autophosphorylation of activation loop tyrosines regulates signaling by the TRK nerve growth factor receptor
modified[InstanceEdit:189699] Jassal, Bijay, 2006-12-01
[InstanceEdit:201381] Gopinathrao, G, 2007-08-07 14:35:20
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameTrk receptor autophosphorylates
output[Complex:181836] Activated Trk receptor complex [plasma membrane] [Rattus norvegicus]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
releaseDate2005-06-13
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48895] Rattus norvegicus
stableIdentifier[StableIdentifier:359320] R-RNO-181812.3
summation[Summation:167061] NGF binding induces a conformational change in TRKA, which e...
(inferredFrom)[Reaction:166544] TrkA receptor autophosphorylates [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by Trk receptor autophosphorylates (181812)