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Details on Person Shc, complexed with TrkA, is Tyrosine-phosphorylated

Class:IdReaction:181799
_displayNameShc, complexed with TrkA, is Tyrosine-phosphorylated
_doReleaseTRUE
_timestamp2011-11-23 11:11:30
authored[InstanceEdit:181805] Jassal, Bijay, 2006-06-20
catalystActivity[CatalystActivity:181837] transmembrane receptor protein tyrosine kinase activity of p-Trk receptor:Shc [plasma membrane]
compartment[Compartment:876] plasma membrane
created[InstanceEdit:181805] Jassal, Bijay, 2006-06-20
edited[InstanceEdit:181805] Jassal, Bijay, 2006-06-20
input[Complex:181802] p-Trk receptor:Shc [plasma membrane] [Rattus norvegicus]
literatureReference[LiteratureReference:181800] Role of Shc in the activation of Ras in response to epidermal growth factor and nerve growth factor
[LiteratureReference:181847] Nerve growth factor induced stimulation of Ras requires Trk interaction with Shc but does not involve phosphoinositide 3-OH kinase
modified[InstanceEdit:187730] Jassal, Bijay, 2006-09-21
[InstanceEdit:189699] Jassal, Bijay, 2006-12-01
[InstanceEdit:189835] Jassal, Bijay, 2006-12-07
[InstanceEdit:1807963] Jassal, B, 2011-10-24
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameShc, complexed with TrkA, is Tyrosine-phosphorylated
output[Complex:181824] NGF dimer:Phosphorylated Trk receptor dimer:Phospho-SHC [plasma membrane] [Rattus norvegicus]
releaseDate2007-12-11
reviewed[InstanceEdit:202668] Greene, LA, 2007-11-08 15:39:37
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48895] Rattus norvegicus
stableIdentifier[StableIdentifier:2016408] R-RNO-181799.2
summation[Summation:1807962] The human event is deduced on the basis of experiments in ra...
(inferredFrom)[Reaction:167019] SHC, complexed with TrkA, is tyrosine-phosphorylated [Homo sapiens]
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