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Details on Person The signal peptide is excised from pre-pro-NGF

Class:Id	Reaction:181788
_displayName	The signal peptide is excised from pre-pro-NGF
_doRelease	TRUE
_timestamp	2016-11-10 00:54:47
catalystActivity	[CatalystActivity:181807] serine-type endopeptidase activity of convertase (Calcium dependant) [endoplasmic reticulum lumen]
compartment	[Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:181805] Jassal, Bijay, 2006-06-20
input	[DefinedSet:181832] pre-pro-NGF precursor [endoplasmic reticulum lumen] [Mus musculus]
literatureReference	[LiteratureReference:167035] Processing and secretion of nerve growth factor: expression in mammalian cells with a vaccinia virus vector [LiteratureReference:167059] Dissociation equilibrium constant of beta nerve growth factor
modified	[InstanceEdit:187008] Jassal, Bijay, 2006-09-07 [InstanceEdit:189699] Jassal, Bijay, 2006-12-01 [InstanceEdit:201381] Gopinathrao, G, 2007-08-07 14:35:20 [InstanceEdit:211746] Jassal, B, 2008-02-08 11:38:28 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	The signal peptide is excised from pre-pro-NGF
output	[DefinedSet:187019] pro-NGF precursor [endoplasmic reticulum lumen] [Mus musculus]
releaseDate	2005-06-13
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:359644] R-MMU-181788.3
summation	[Summation:167040] Pre-pro- precursors of the neurotrophins NGF, BDNF, NT-3, NT...
(inferredFrom)	[Reaction:166539] pro-neurotrophin is cleaved to form NGF [Homo sapiens] [Reaction:187045] The signal peptide is excised from beta-NGF pre-pro-precursor [Homo sapiens]
(precedingEvent)	[Reaction:181822] pro-NGF dimerizes [Mus musculus]
(updatedInstance)	[_UpdateTracker:9792108] Update Tracker - [Reaction:181788] The signal peptide is excised from pre-pro-NGF - v24:[addSummation]
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No pathways have been reviewed or authored by The signal peptide is excised from pre-pro-NGF (181788)