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Details on Person botE HC disulfide bonded [plasma membrane]

Class:Id	EntityWithAccessionedSequence:181571
_displayName	botE HC disulfide bonded [plasma membrane]
_timestamp	2020-10-08 22:00:55
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:181561] Gopinathrao, G, 2006-06-14 16:40:11
disease	[Disease:3632909] botulism
endCoordinate	1251
goCellularComponent	[GO_CellularComponent:6485] host cell plasma membrane
hasModifiedResidue	[InterChainCrosslinkedResidue:5228672] Inter-chain Crosslink via L-cystine (cross-link) at 426 and 412
literatureReference	[LiteratureReference:5228677] Botulinum neurotoxin type E fragmented with endoproteinase Lys-C reveals the site trypsin nicks and homology with tetanus neurotoxin
modified	[InstanceEdit:190033] Gopinathrao, G, 2006-12-13 17:03:37 [InstanceEdit:2395917] D'Eustachio, P, 2012-07-05 [InstanceEdit:5228945] D'Eustachio, Peter, 2014-01-14 [InstanceEdit:5324685] D'Eustachio, Peter, 2014-02-17 [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9689079] Cook, Justin, 2020-05-15 [InstanceEdit:9689079] Cook, Justin, 2020-05-15 [InstanceEdit:9704403] D'Eustachio, Peter, 2020-10-08 [InstanceEdit:9715688] Shorser, Solomon, 2021-02-17 [InstanceEdit:9729976] Shorser, Solomon, 2021-05-05 [InstanceEdit:9750461] Weiser, JD, 2021-08-11 [InstanceEdit:9757984] Weiser, JD, 2021-11-08 [InstanceEdit:9767390] Wright, Adam, 2022-02-25 [InstanceEdit:9773515] Weiser, Joel, 2022-05-04 [InstanceEdit:9909910] Weiser, Joel, 2024-05-14 [InstanceEdit:9917728] Weiser, Joel, 2024-08-09 [InstanceEdit:9926726] Weiser, Joel, 2024-11-03 [InstanceEdit:9939161] Weiser, Joel, 2025-02-21 [InstanceEdit:9948552] Weiser, Joel, 2025-05-21 [InstanceEdit:9963749] Weiser, Joel, 2025-08-15 [InstanceEdit:9970792] Weiser, Joel, 2025-10-31 [InstanceEdit:9983308] Weiser, Joel, 2026-02-22 [InstanceEdit:9989150] Weiser, Joel, 2026-05-15
name	botE HC disulfide bonded BoNT/E HC disulfide bonded BoNT Heavy chain Type E
referenceEntity	[ReferenceGeneProduct:181453] UniProt:Q00496 botE [Clostridium botulinum]
species	[Species:168825] Clostridium botulinum
stableIdentifier	[StableIdentifier:365821] R-CBO-181571.20
startCoordinate	423
(hasComponent)	[Complex:5228955] BoNT/E HC:LC dimer [plasma membrane] [Clostridium botulinum]
(replacementInstances)	[_Deleted:5251010] Deletion of instance: 181563
(updatedInstance)	[_UpdateTracker:9889215] Update Tracker - [EntityWithAccessionedSequence:181571] botE HC disulfide bonded [plasma membrane] - v48:[addDisease, addHasModifiedResidue, addLiteratureReference, addName, modifyEndCoordinate, modifyStartCoordinate] [_UpdateTracker:9901688] Update Tracker - [EntityWithAccessionedSequence:181571] botE HC disulfide bonded [plasma membrane] - v75:[modifyName]
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No pathways have been reviewed or authored by botE HC disulfide bonded [plasma membrane] (181571)