Query author contributions in Reactome
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Details on Person TLR2 and TLR4 recognize different bacterial cell wall compon...
| Class:Id | Summation:181445 |
|---|---|
| _displayName | TLR2 and TLR4 recognize different bacterial cell wall compon... |
| _timestamp | 2011-07-14 15:32:36 |
| created | [InstanceEdit:181446] de Bono, B, 2006-06-13 11:06:35 |
| modified | [InstanceEdit:181936] de Bono, B, 2006-07-03 10:27:58 [InstanceEdit:181939] D'Eustachio, P, 2006-07-03 21:35:13 [InstanceEdit:1449548] D'Eustachio, P, 2011-07-14 |
| text | TLR2 and TLR4 recognize different bacterial cell wall components. While TLR4 is trained onto Gram-negative lipopolysaccharide components, TLR2 - in combination with TLR6 - plays a major role in recognizing peptidoglycan wall products from Gram-positive bacteria, as well as Mycobacterial diacylated lipopeptides. In particular, TLR6 appears to participate in discriminating the subtle differences between dipalmitoyl and tripalmitoyl cysteinyl residues (Okusawa et al. 2004). |
| (summation) | [Pathway:168188] Toll Like Receptor TLR6:TLR2 Cascade [Homo sapiens] |
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No pathways have been reviewed or authored by TLR2 and TLR4 recognize different bacterial cell wall compon... (181445)
