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Details on Person Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane]

Class:Id	DefinedSet:181230
_displayName	Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane]
_timestamp	2020-12-01 03:21:00
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:181229] de Bono, B, 2006-06-08 12:44:54
hasMember	[Complex:181226] TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] [Homo sapiens] [Complex:181410] TLR6:TLR2:ligand:CD14:CD36 [plasma membrane] [Homo sapiens] [Complex:166850] TLR4:LY96:LPS:CD14 [plasma membrane] [Homo sapiens] [DefinedSet:9708724] TLR4:LY96:endogenous ligand [plasma membrane] [Homo sapiens] [Complex:5432869] HC23,45-HMGB1:TLR4:LY96 [plasma membrane] [Homo sapiens] [Complex:6805997] S100A1:TLR4:LY96 [plasma membrane] [Homo sapiens] [Complex:5432865] TLR4:LY96:S100A8:S100A9 [plasma membrane] [Homo sapiens] [Complex:8870679] TLR4:LY96:cleaved fibrinogen [plasma membrane] [Homo sapiens]
modified	[InstanceEdit:181393] de Bono, B, 2006-06-09 10:09:39 [InstanceEdit:181412] de Bono, B, 2006-06-09 11:20:10 [InstanceEdit:181939] D'Eustachio, P, 2006-07-03 21:35:13 [InstanceEdit:188022] de Bono, B, 2006-09-29 15:49:22 [InstanceEdit:188062] de Bono, B, 2006-09-30 09:24:29 [InstanceEdit:188115] de Bono, B, 2006-09-30 13:42:43 [InstanceEdit:188152] de Bono, B, 2006-09-30 14:34:13 [InstanceEdit:188153] de Bono, B, 2006-09-30 14:35:56 [InstanceEdit:188154] de Bono, B, 2006-09-30 14:38:38 [InstanceEdit:188169] de Bono, B, 2006-09-30 14:59:12 [InstanceEdit:188203] de Bono, B, 2006-10-02 08:56:17 [InstanceEdit:188668] de Bono, B, 2006-10-20 12:14:54 [InstanceEdit:188694] de Bono, B, 2006-10-24 12:19:00 [InstanceEdit:500229] Jupe, S, 2010-02-01 [InstanceEdit:937085] Shamovsky, V, 2010-08-25 [InstanceEdit:1097343] Matthews, L, 2010-11-30 [InstanceEdit:2008117] Shamovsky, V, 2011-11-21 [InstanceEdit:2559471] Shamovsky, V, 2012-11-02 [InstanceEdit:8948875] Matthews, Lisa, 2016-11-17 [InstanceEdit:9628833] Shamovsky, Veronica, 2018-11-13 [InstanceEdit:9708727] Shamovsky, Veronica, 2020-12-01
name	Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer
relatedSpecies	[Species:181384] Chlamydia trachomatis [Species:180800] Neisseria meningitidis serogroup B
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:366250] R-HSA-181230.4
(hasComponent)	[Complex:2201325] activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] [Homo sapiens] [Complex:2201331] TIRAP:PI(4,5)P2:BTK:activated TLR2/4 [plasma membrane] [Homo sapiens] [Complex:2559411] TIRAP:PI(4,5)P2:activated TLR2/4 [plasma membrane] [Homo sapiens]
(input)	[Reaction:2201316] Activated TLR2/4 interacts with MAL (TIRAP) [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9863792] Update Tracker - [DefinedSet:181230] Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] - v20:[updateContainedMemberOrCandidate] [_UpdateTracker:9867629] Update Tracker - [DefinedSet:181230] Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] - v25:[updateContainedMemberOrCandidate] [_UpdateTracker:9868757] Update Tracker - [DefinedSet:181230] Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] - v32:[updateContainedMemberOrCandidate] [_UpdateTracker:9871062] Update Tracker - [DefinedSet:181230] Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] - v39:[removeCompartment, updateContainedMemberOrCandidate] [_UpdateTracker:9871986] Update Tracker - [DefinedSet:181230] Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] - v41:[updateContainedMemberOrCandidate] [_UpdateTracker:9873013] Update Tracker - [DefinedSet:181230] Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] - v42:[updateContainedMemberOrCandidate] [_UpdateTracker:9873671] Update Tracker - [DefinedSet:181230] Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] - v43:[add_removeHasMember, updateContainedMemberOrCandidate] [_UpdateTracker:9889438] Update Tracker - [DefinedSet:181230] Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] - v49:[updateContainedMemberOrCandidate] [_UpdateTracker:9891443] Update Tracker - [DefinedSet:181230] Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] - v52:[updateContainedMemberOrCandidate] [_UpdateTracker:9892741] Update Tracker - [DefinedSet:181230] Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] - v54:[updateContainedMemberOrCandidate] List all 14 refering instances
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No pathways have been reviewed or authored by Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (181230)