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Details on Person Deamination of C residues during synthesis of HIV-1 reverse transcript minus-strand

Class:Id	Reaction:180632
_displayName	Deamination of C residues during synthesis of HIV-1 reverse transcript minus-strand
_doRelease	TRUE
_timestamp	2014-12-12 21:43:59
authored	[InstanceEdit:180926] Matthews, L, 2006-06-07 20:09:24
catalystActivity	[CatalystActivity:180615] dCTP deaminase activity of APOBEC3G [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:180635] Matthews, L, 2006-05-23 14:14:28
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
edited	[InstanceEdit:192229] Matthews, L, 2007-01-30 11:27:41
figure	[Figure:192281] /figures/vif2.jpg
input	[SimpleEntity:29356] H2O [cytosol] [Complex:180616] APOBEC3G:RTC with minus sssDNA:tRNA primer:RNA template [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:180669] Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome [LiteratureReference:180678] The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA
modified	[InstanceEdit:180757] Matthews, L, 2006-06-02 10:48:27 [InstanceEdit:182370] Matthews, L, 2006-07-07 14:32:37 [InstanceEdit:182673] Matthews, L, 2006-07-11 22:16:59 [InstanceEdit:182901] Matthews, L, 2006-07-20 22:59:39 [InstanceEdit:182905] Matthews, L, 2006-07-20 23:13:38 [InstanceEdit:188909] Gopinathrao, G, 2006-10-30 15:46:37 [InstanceEdit:192263] Matthews, L, 2007-01-30 13:58:17 [InstanceEdit:192280] Matthews, L, 2007-01-30 22:18:28 [InstanceEdit:192285] Matthews, L, 2007-01-30 22:45:27 [InstanceEdit:192295] Matthews, L, 2007-01-30 23:21:25 [InstanceEdit:193854] Matthews, L, 2007-02-28 11:18:59 [InstanceEdit:5621512] Matthews, Lisa, 2014-08-29 [InstanceEdit:5656435] Gillespie, Marc E, 2014-12-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Deamination of C residues during synthesis of HIV-1 reverse transcript minus-strand
output	[SimpleEntity:29382] NH3 [cytosol] [Complex:180744] APOBEC3G:RTC with deaminated minus sssDNA:tRNA primer:RNA template [cytosol] [Homo sapiens]
precedingEvent	[Reaction:180634] Association of APOBEC3G with single-stranded region of forming HIV-1 minus strand [Homo sapiens]
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2007-02-20
reviewed	[InstanceEdit:192288] Mulder, L, 2007-01-30 22:57:00 [InstanceEdit:192290] Simon, V, 2007-01-30 23:07:12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:358930] R-HSA-180632.2
summation	[Summation:180706] During reverse transcription, APOBEC3G-mediated minus-strand...
(hasEvent)	[Pathway:180689] APOBEC3G mediated resistance to HIV-1 infection [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9786810] Update Tracker - [Reaction:180632] Deamination of C residues during synthesis of HIV-1 reverse transcript minus-strand - v48:[modifyText] [_UpdateTracker:9789674] Update Tracker - [Reaction:180632] Deamination of C residues during synthesis of HIV-1 reverse transcript minus-strand - v37:[modifyText]
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