Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person RBX1 [cytosol]

Class:IdEntityWithAccessionedSequence:180582
_displayNameRBX1 [cytosol]
_timestamp2012-02-21 17:41:23
compartment[Compartment:70101] cytosol
created[InstanceEdit:180586] Matthews, L, 2006-05-23 13:59:44
endCoordinate108
modified[InstanceEdit:2130745] Rothfels, K, 2012-02-21
nameRBX1
ROC1
referenceEntity[ReferenceGeneProduct:99731] UniProt:P62877 RBX1 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:369773] R-HSA-180582.1
startCoordinate2
(activeUnit)[CatalystActivity:1504214] ubiquitin protein ligase activity of DVL:CUL3:KLHL12:RBX1 [cytosol]
[CatalystActivity:5658421] ubiquitin protein ligase activity of KBTBD7:CUL3:RBX1 [cytosol]
[CatalystActivity:8932320] ubiquitin protein ligase activity of KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol]
[CatalystActivity:8952619] NEDD8 transferase activity of NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol]
[CatalystActivity:8952624] NEDD8 transferase activity of NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol]
[CatalystActivity:8952632] NEDD8 transferase activity of NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol]
[CatalystActivity:9759171] ubiquitin protein ligase activity of p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol]
[CatalystActivity:9766646] ubiquitin protein ligase activity of SESN1,2:ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol]
(hasComponent)[Complex:180596] Cul5-SCF complex [cytosol] [Homo sapiens]
[Complex:206748] BTRC:CUL1:RBX1:SKP1 [cytosol] [Homo sapiens]
[Complex:206940] Phospho Gli3:beta-TrCP:Skp1:Cul1:Rbx1:E2 [cytosol] [Homo sapiens]
[Complex:976074] RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] [Homo sapiens]
[Complex:976093] RBX1-CUL2-EloB,C-VHL [cytosol] [Homo sapiens]
[Complex:976101] RBX1:CUL3:BTB [cytosol] [Homo sapiens]
[Complex:976110] SCF E3 ubiquitin ligase [cytosol] [Homo sapiens]
[Complex:1504195] CUL3:KLHL12:RBX1 [cytosol] [Homo sapiens]
[Complex:5658416] KBTBD7:CUL3:RBX1 [cytosol] [Homo sapiens]
[Complex:8854030] SKP1:CUL1:RBX1:FBXL7 [cytosol] [Homo sapiens]
List all 34 refering instances
(input)[Reaction:8854052] Formation of the SCF-FBXL7 complex [Homo sapiens]
[Reaction:9974206] NSP1 binds the Cul3-RING ligase (CRL3) complex [Homo sapiens]
(output)[BlackBoxEvent:9974797] 20S proteasome-mediated degradation of PolyUb-BTRC and NSP1 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9871403] Update Tracker - [EntityWithAccessionedSequence:180582] RBX1 [cytosol] - v40:[modifyEndCoordinate, modifyName, modifyStartCoordinate]
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No pathways have been reviewed or authored by RBX1 [cytosol] (180582)
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