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Details on Person Multi-ubiquitination of APOBEC3G

Class:Id	Reaction:180540
_displayName	Multi-ubiquitination of APOBEC3G
_doRelease	TRUE
_timestamp	2014-12-12 21:44:23
authored	[InstanceEdit:180020] Matthews, L, 2006-05-15 23:53:25
catalystActivity	[CatalystActivity:180584] ubiquitin-protein transferase activity of APOBEC3G:Vif:Cul5:SCF complex [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:180586] Matthews, L, 2006-05-23 13:59:44
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
edited	[InstanceEdit:192229] Matthews, L, 2007-01-30 11:27:41
input	[Complex:180549] APOBEC3G:Vif:Cul5:SCF complex [cytosol] [Homo sapiens] [DefinedSet:113595] Ub [cytosol] [Homo sapiens] [DefinedSet:113595] Ub [cytosol] [Homo sapiens] [DefinedSet:113595] Ub [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:180741] Ubiquitination of APOBEC3G by an HIV-1 Vif-Cullin5-Elongin B-Elongin C complex is essential for Vif function
modified	[InstanceEdit:180762] Matthews, L, 2006-06-02 10:50:18 [InstanceEdit:182673] Matthews, L, 2006-07-11 22:16:59 [InstanceEdit:182902] Matthews, L, 2006-07-20 23:04:44 [InstanceEdit:182905] Matthews, L, 2006-07-20 23:13:38 [InstanceEdit:188431] Gopinathrao, G, 2006-10-12 14:53:00 [InstanceEdit:188910] Gopinathrao, G, 2006-10-30 15:47:09 [InstanceEdit:192267] Matthews, L, 2007-01-30 13:59:10 [InstanceEdit:192296] Matthews, L, 2007-01-30 23:22:09 [InstanceEdit:193854] Matthews, L, 2007-02-28 11:18:59 [InstanceEdit:5621512] Matthews, Lisa, 2014-08-29 [InstanceEdit:5656435] Gillespie, Marc E, 2014-12-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Multi-ubiquitination of APOBEC3G
output	[Complex:180577] multi-ubiquitinated APOBEC3G:Vif:Cul5:SCF complex [cytosol] [Homo sapiens]
precedingEvent	[Reaction:180555] Association of APOBEC3G:Vif with the Cul5-SCF complex [Homo sapiens] [Reaction:180602] Association of Vif with APOBEC3G [Homo sapiens]
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2007-02-20
reviewed	[InstanceEdit:192288] Mulder, L, 2007-01-30 22:57:00 [InstanceEdit:192290] Simon, V, 2007-01-30 23:07:12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:359187] R-HSA-180540.2
summation	[Summation:180675] APOBEC3G is multi-ubiquitinated by the Vif-Cul5-SCF complex.
(hasEvent)	[Pathway:180585] Vif-mediated degradation of APOBEC3G [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:180603] Proteosome-mediated degradation of APOBEC3G [Homo sapiens]
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