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Details on Person A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

Class:IdLiteratureReference:180533
_displayNameA novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif
_timestamp2006-05-23 14:00:39
author[Person:180541] Margottin, F
[Person:180544] Bour, SP
[Person:180587] Durand, H
[Person:180564] Selig, L
[Person:180547] Benichou, S
[Person:180604] Richard, V
[Person:180595] Thomas, D
[Person:180529] Strebel, K
[Person:180558] Benarous, Richard
created[InstanceEdit:180586] Matthews, L, 2006-05-23 13:59:44
journalMol Cell
pages565-74
pubMedIdentifier9660940
titleA novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif
volume1
year1998
(literatureReference)[BlackBoxEvent:180573] Degradation of ubiquitinated CD4 [Homo sapiens]
[Reaction:180591] Vpu:CD4 associates with beta-TrCP [Homo sapiens]
[Reaction:180597] Ubiquitination of CD4 by Vpu:CD4:beta-TrCP:SKP1 complex [Homo sapiens]
[Reaction:180599] The Vpu:CD4:beta-TrCP complex recruits SKP1 [Homo sapiens]
[Reaction:180606] Association of Vpu with CD4 [Homo sapiens]
[Summation:180600] Vpu is expressed in the ER and associates with a membrane-pr...
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