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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person CUL5 [cytosol]

Class:IdEntityWithAccessionedSequence:180528
_displayNameCUL5 [cytosol]
_timestamp2025-02-17 23:13:33
compartment[Compartment:70101] cytosol
created[InstanceEdit:180586] Matthews, L, 2006-05-23 13:59:44
endCoordinate780
modified[InstanceEdit:1916704] Orlic-Milacic, M, 2011-11-02
[InstanceEdit:9938525] D'Eustachio, Peter, 2025-02-17
nameCUL5
Cullin-5
referenceEntity[ReferenceGeneProduct:67084] UniProt:Q93034 CUL5 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:363535] R-HSA-180528.2
startCoordinate1
(hasComponent)[Complex:180596] Cul5-SCF complex [cytosol] [Homo sapiens]
[Complex:976109] RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] [Homo sapiens]
[Complex:8863234] CRL5 E3 ubiquitin ligase [cytosol] [Homo sapiens]
[Complex:9705723] SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 [endocytic vesicle membrane] [Homo sapiens]
[Complex:9729683] SOCS3:ELOB:ELOC:CUL5:RNF7 [cytosol] [Homo sapiens]
(input)[Reaction:9705729] SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 binds CUL5, ELOB, ELOC, RNF7 [Homo sapiens]
(output)[BlackBoxEvent:9705738] SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 [Homo sapiens]
(physicalEntity)[CatalystActivity:1918088] ubiquitin-protein transferase activity of CUL5 [cytosol]
(updatedInstance)[_UpdateTracker:9871007] Update Tracker - [EntityWithAccessionedSequence:180528] CUL5 [cytosol] - v39:[modifyEndCoordinate, modifyName, modifyStartCoordinate]
[_UpdateTracker:9939996] Update Tracker - [EntityWithAccessionedSequence:180528] CUL5 [cytosol] - v92:[modifyStartCoordinate]
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No pathways have been reviewed or authored by CUL5 [cytosol] (180528)
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