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Details on Person As inferred from mouse homologs, RORA binds RRE DNA elements...
| Class:Id | Summation:1801589 |
|---|---|
| _displayName | As inferred from mouse homologs, RORA binds RRE DNA elements... |
| _timestamp | 2025-01-22 18:27:29 |
| created | [InstanceEdit:1801584] May, B, 2011-10-23 |
| modified | [InstanceEdit:5663275] May, Bruce, 2015-01-16 [InstanceEdit:9734261] May, Bruce, 2021-06-16 [InstanceEdit:9934287] May, Bruce, 2025-01-07 [InstanceEdit:9936399] May, Bruce, 2025-01-22 |
| text | As inferred from mouse homologs, RORA binds RRE DNA elements in the promoter of CPT1A and recruits the coactivators PGC-1alpha (PPARGC1A) and p300 (EP300, a histone acetylase) to enhance transcription of CPT1A, which encodes Carnitine O-palmitoyltransferase 1, an enzyme required for uptake and beta oxidation of fatty acids by mitochondria. |
| (summation) | [Reaction:5663264] RORA and EP300 bind the Carnitine O-palmitoyltransferase 1 (CPT1A) gene [Homo sapiens] |
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No pathways have been reviewed or authored by As inferred from mouse homologs, RORA binds RRE DNA elements... (1801589)
