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Details on Person Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2

Class:Id	LiteratureReference:179827
_displayName	Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2
_timestamp	2012-11-25 22:58:02
author	[Person:179897] Chardin, P [Person:179807] Camonis, JH [Person:179839] Gale, NW [Person:179874] Van Aelst, L [Person:179800] Schlessinger, J [Person:2396583] Wigler, Michael H [Person:179826] Bar-Sagi, Dafna
created	[InstanceEdit:179808] Jassal, Bijay, 2006-05-09
journal	Science
modified	[InstanceEdit:2671780] D'Eustachio, P, 2012-11-25
pages	1338-43
pubMedIdentifier	8493579
title	Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2
volume	260
year	1993
(literatureReference)	[Reaction:177936] GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR [Homo sapiens] [Reaction:177938] SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) [Homo sapiens] [Reaction:177945] SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) [Homo sapiens] [Reaction:392054] NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras [Homo sapiens] [Reaction:1225961] Phosphorylated SHC1 in complex with ligand-responsive p-6Y-EGFR mutants recruits GRB2:SOS1 complex [Homo sapiens] [Reaction:2179407] SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) [Homo sapiens] [Reaction:2730844] Interaction of GRB2:SOS complex with p-SHC1 [Homo sapiens] [Reaction:5637798] Phosphorylated SHC1 in complex with p-5Y-EGFRvIII recruits GRB2:SOS1 complex [Homo sapiens] [Reaction:5654392] Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange [Homo sapiens] [Reaction:5654402] Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange [Homo sapiens] List all 29 refering instances
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