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Details on Person smooth endoplasmic reticulum

Class:Id	Compartment:17960
_displayName	smooth endoplasmic reticulum
_timestamp	2018-04-19 17:11:26
accession	0005790
definition	The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER.
instanceOf	[GO_CellularComponent:70260] endoplasmic reticulum [GO_CellularComponent:159960] intracellular membrane-bounded organelle [GO_CellularComponent:159959] membrane-bounded organelle [GO_CellularComponent:159955] organelle [GO_CellularComponent:9666329] cellular anatomical structure [GO_CellularComponent:357] cellular_component [GO_CellularComponent:159957] intracellular organelle [GO_CellularComponent:159955] organelle [GO_CellularComponent:9666329] cellular anatomical structure [GO_CellularComponent:357] cellular_component
modified	[InstanceEdit:160533] Schmidt, EE, 2005-03-23 05:24:35 [InstanceEdit:162607] Schmidt, EE, 2005-04-01 11:06:09 [InstanceEdit:171322] Schmidt, EE, 2006-02-06 10:50:16 [InstanceEdit:258122] Kanapin, EE, 2008-03-27 12:15:20 [InstanceEdit:357819] Kanapin, EE, 2008-06-18 10:45:39 [InstanceEdit:376438] Kanapin, EE, 2008-09-08 10:23:04 [InstanceEdit:383393] Kanapin, AA, 2008-11-26 13:49:44 [InstanceEdit:396309] Kanapin, EE, 2009-03-09 13:26:57 [InstanceEdit:422569] Kanapin, EE [InstanceEdit:436347] Kanapin, EE [InstanceEdit:447572] Kanapin, EE [InstanceEdit:526073] Kanapin, AA [InstanceEdit:528085] Kanapin, AA [InstanceEdit:615500] Kanapin, AA [InstanceEdit:797782] Kanapin, AA [InstanceEdit:937668] Yung, CK [InstanceEdit:1042299] Yung, CK [InstanceEdit:1220942] Yung, CK [InstanceEdit:1301009] Yung, CK [InstanceEdit:1301023] Yung, CK [InstanceEdit:1552540] Yung, CK [InstanceEdit:1996004] Yung, CK [InstanceEdit:2132408] Weiser, JD [InstanceEdit:2133145] Weiser, JD [InstanceEdit:2266118] Weiser, JD [InstanceEdit:2266147] Weiser, JD [InstanceEdit:2454362] Weiser, JD [InstanceEdit:2455542] Weiser, JD [InstanceEdit:2587907] Weiser, JD [InstanceEdit:3132285] Weiser, JD [InstanceEdit:3445953] Weiser, JD [InstanceEdit:4341211] Weiser, JD [InstanceEdit:5083267] Weiser, JD [InstanceEdit:5263134] Weiser, JD [InstanceEdit:8866303] Jassal, Bijay, 2016-03-30 [InstanceEdit:9644776] Wu, G, 2019-04-20 [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9689214] Cook, Justin, 2020-05-15 [InstanceEdit:9715950] Shorser, Solomon, 2021-02-17 [InstanceEdit:9730069] Shorser, Solomon, 2021-05-05 [InstanceEdit:9750511] Weiser, JD, 2021-08-11 [InstanceEdit:9758049] Weiser, JD, 2021-11-08 [InstanceEdit:9767446] Wright, Adam, 2022-02-25 [InstanceEdit:9773560] Weiser, Joel, 2022-05-04 [InstanceEdit:9910546] Weiser, Joel, 2024-05-14 [InstanceEdit:9917761] Weiser, Joel, 2024-08-09 [InstanceEdit:9926777] Weiser, Joel, 2024-11-03 [InstanceEdit:9939260] Weiser, Joel, 2025-02-21 [InstanceEdit:9948590] Weiser, Joel, 2025-05-21 [InstanceEdit:9963890] Weiser, Joel, 2025-08-15 [InstanceEdit:9970828] Weiser, Joel, 2025-10-31 [InstanceEdit:9983368] Weiser, Joel, 2026-02-22 [InstanceEdit:9989188] Weiser, Joel, 2026-05-15
name	smooth endoplasmic reticulum
referenceDatabase	[ReferenceDatabase:1] GO
surroundedBy	[Compartment:70101] cytosol [Compartment:947587] cytoplasmic side of plasma membrane [Compartment:876] plasma membrane [Compartment:984] extracellular region [Compartment:24781] apical plasma membrane [Compartment:984] extracellular region [Compartment:24778] basolateral plasma membrane [Compartment:984] extracellular region
(compartment)	[Reaction:76354] Vinyl chloride is oxidized to 2-Chloroethylene oxide [Homo sapiens] [Reaction:76373] N-hydroxylation of 4-aminobiphenyl [Homo sapiens] [Reaction:76386] CYP1A2 S-demethylates 6MMP [Homo sapiens] [Reaction:76392] Acetaldehyde + O₂ + NADPH + H⁺ -> Acetate + H₂O + NADP⁺ [Homo sapiens] [Reaction:76400] Addition of an electron (from either NADPH-cytochrome P450 reductase or cytochrome b5) and proton [Homo sapiens] [Reaction:76401] Addition of molecular oxygen [Homo sapiens] [Reaction:76416] Benzene is hydroxylated to phenol [Homo sapiens] [Reaction:76426] N-atom dealkylation of caffeine [Homo sapiens] [Reaction:76434] Dehalogenation of carbon tetrachloride to form a free radical [Homo sapiens] [Reaction:76453] Coumarin is 7-hydroxylated by CYP2A6 [Homo sapiens] List all 58 refering instances
(componentOf)	[GO_CellularComponent:78971] smooth endoplasmic reticulum lumen [GO_CellularComponent:161478] smooth endoplasmic reticulum membrane [GO_CellularComponent:9016411] smooth endoplasmic reticulum cisterna
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No pathways have been reviewed or authored by smooth endoplasmic reticulum (17960)