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Details on Person Mitochondrial ECHS1 (enoyl-CoA hydratase) hexamer catalyzes ...

Class:IdSummation:178949
_displayNameMitochondrial ECHS1 (enoyl-CoA hydratase) hexamer catalyzes ...
_timestamp2020-01-03 15:43:22
created[InstanceEdit:179407] Gopinathrao, G, 2006-04-27 13:13:48
modified[InstanceEdit:181932] D'Eustachio, P, 2006-06-27 13:49:34
[InstanceEdit:9672919] D'Eustachio, Peter, 2020-01-03
textMitochondrial ECHS1 (enoyl-CoA hydratase) hexamer catalyzes the reversible addition of water to MACR-CoA (methacrylyl-CoA) to form bHIB-CoA (beta-hydroxybutyryl-CoA). Partially purified ECHS1 catalyzes this reaction with moderate efficiency in vitro, and patients deficient in the enzyme accumulate and excrete MACR-CoA (Yamada et al. 2015).
(summation)[Reaction:70870] ECHS1 hydrates methacrylyl-CoA [Homo sapiens]
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