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Details on Person Cytosolic kynurenine 3-monooxygenase (KMO) catalyzes the rea...

Class:IdSummation:178923
_displayNameCytosolic kynurenine 3-monooxygenase (KMO) catalyzes the rea...
_timestamp2026-01-12 23:13:23
created[InstanceEdit:179407] Gopinathrao, G, 2006-04-27 13:13:48
modified[InstanceEdit:198560] D'Eustachio, P, 2007-06-22 18:24:32
[InstanceEdit:9978940] D'Eustachio, Peter, 2026-01-12
textCytosolic kynurenine 3-monooxygenase (KMO) catalyzes the reaction of L-kynurenine, NADPH + H+, and O2 to form 3-hydroxy-L-kynurenine, NADP+, and H2O (Breton et al. 2000). The localization of KMO to the outer mitochondrial membrane is inferred from studies of the enzyme in rat liver mitochondria (Okamoto et al. 1967).
(summation)[Reaction:71200] kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O [Homo sapiens]
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