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Details on Person Mitochondrial isovaleryl dehydrogenase (IVD) catalyzes the r...

Class:IdSummation:178922
_displayNameMitochondrial isovaleryl dehydrogenase (IVD) catalyzes the r...
_timestamp2024-07-31 18:59:31
created[InstanceEdit:179407] Gopinathrao, G, 2006-04-27 13:13:48
modified[InstanceEdit:508306] D'Eustachio, P, 2010-02-11
[InstanceEdit:9914761] Rothfels, Karen, 2024-06-27
[InstanceEdit:9917207] Rothfels, Karen, 2024-07-31
textMitochondrial isovaleryl dehydrogenase (IVD) catalyzes the reaction of isovaleryl-CoA and FAD to form beta-methylcrotonyl-CoA and FADH2 (Finocchiaro et al. 1978; Rhead and Tanaka 1980). Crystallographic studies demonstrated the existence of a tetramer of IVD polypeptides lacking an amino-terminal mitochondrial targeting sequence (Tiffany et al. 1997).
(summation)[Reaction:70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 [Homo sapiens]
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