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Query author contributions in Reactome

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Details on Person In the second step in the formation of glutathione, gamma-gl...

Class:IdSummation:178803
_displayNameIn the second step in the formation of glutathione, gamma-gl...
_timestamp2014-06-25 13:15:53
created[InstanceEdit:179407] Gopinathrao, G, 2006-04-27 13:13:48
modified[InstanceEdit:1247945] Jassal, B, 2011-04-08
[InstanceEdit:5602968] Jassal, Bijay, 2014-06-25
textIn the second step in the formation of glutathione, gamma-glutamylcysteine (gGluCys) ligates with glycine (Gly) to form glutathione (GSH) (Gali & Board 1995). This reaction is catalysed by glutathione synthetase (GSS), a homodimeric enzyme present in the cytosol which requires one Mg2+ cofactor per subunit for activity (Polekhina et al. 1999).
(summation)[Reaction:174394] GSS:Mg2+ dimer synthesizes GSH [Homo sapiens]
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