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Details on Person FADD recruits caspase-10 precursor (pro-caspase-10) to FASL:...

Class:IdSummation:178763
_displayNameFADD recruits caspase-10 precursor (pro-caspase-10) to FASL:...
_timestamp2012-11-09 20:36:03
created[InstanceEdit:179407] Gopinathrao, G, 2006-04-27 13:13:48
literatureReference[LiteratureReference:141306] Caspase-10 is an initiator caspase in death receptor signaling
[LiteratureReference:141314] Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8
modified[InstanceEdit:2566509] Orlic-Milacic, M, 2012-11-09
textFADD recruits caspase-10 precursor (pro-caspase-10) to FASL:FAS receptor trimer (Wang et al. 2001, Sprick et al. 2002).
(summation)[Reaction:141310] FASL:FAS Receptor Trimer:FADD complex binds procaspase-10 [Homo sapiens]
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No pathways have been reviewed or authored by FADD recruits caspase-10 precursor (pro-caspase-10) to FASL:... (178763)