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Details on Person At the beginning of this reaction, 1 molecule of 'RNA primer...
| Class:Id | Summation:178666 |
| _displayName | At the beginning of this reaction, 1 molecule of 'RNA primer... |
| _timestamp | 2017-04-10 11:15:01 |
| created | [InstanceEdit:179407] Gopinathrao, G, 2006-04-27 13:13:48 |
| literatureReference | [LiteratureReference:8984666] A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome [LiteratureReference:8984656] Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing [LiteratureReference:8984605] Human Mcm10 regulates the catalytic subunit of DNA polymerase-alpha and prevents DNA damage during replication [LiteratureReference:169462] Primer utilization by DNA polymerase alpha-primase is influenced by its interaction with Mcm10p |
| modified | [InstanceEdit:8984379] Duenas, Corina, 2017-04-05 [InstanceEdit:8984615] Duenas, Corina, 2017-04-10 |
| text | At the beginning of this reaction, 1 molecule of 'RNA primer-DNA primer:origin duplex' is present. At the end of this reaction, 1 molecule of 'DNA polymerase alpha:primase', and 1 molecule of 'RNA primer-DNA primer:origin duplex with DNA damage' are present. This reaction takes place in the 'nucleus' (Gambus et al. 2009, Remus et al. 2009, Chattopadhyay et al.2007, Fien et al. 2004). |
| (summation) | [Reaction:113504] Detection of damage during initiation of DNA synthesis in S-phase [Homo sapiens] |
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No pathways have been reviewed or authored by At the beginning of this reaction, 1 molecule of 'RNA primer... (178666)