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Details on Person Cytosolic phosphoribosyl pyrophosphate synthetase 1 catalyze...
| Class:Id | Summation:178636 |
|---|---|
| _displayName | Cytosolic phosphoribosyl pyrophosphate synthetase 1 catalyze... |
| _timestamp | 2025-01-06 08:50:47 |
| created | [InstanceEdit:179407] Gopinathrao, G, 2006-04-27 13:13:48 |
| modified | [InstanceEdit:189818] D'Eustachio, P, 2006-12-06 23:20:55 [InstanceEdit:478871] D'Eustachio, P, 2010-01-26 [InstanceEdit:9934059] Stephan, Ralf, 2025-01-06 |
| text | Cytosolic phosphoribosyl pyrophosphate synthetase 1 catalyzes the reaction of D-ribose 5-phosphate and dATP to form 5-phospho-alpha-D-ribose 1-diphosphate and 2'-deoxyadenosine 5'-monophosphate. While phosphoribosyl pyrophosphate synthetase 1 works well with either ATP or dATP as a substrate in vitro, the extent of the dATP reaction in vivo is unclear, as cellular dATP concentrations are normally very low (Fox and Kelley 1971; reviewed in Hove-Jensen et al., 2016). |
| (summation) | [Reaction:111215] PRPS1 dimer pyrophosphorylates R5P using dATP [Homo sapiens] |
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No pathways have been reviewed or authored by Cytosolic phosphoribosyl pyrophosphate synthetase 1 catalyze... (178636)
