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Details on Person Peroxisomal glyceronephosphate O-acyltransferase (GNPAT) cat...
| Class:Id | Summation:178382 |
|---|---|
| _displayName | Peroxisomal glyceronephosphate O-acyltransferase (GNPAT) cat... |
| _timestamp | 2009-02-06 21:28:46 |
| created | [InstanceEdit:179407] Gopinathrao, G, 2006-04-27 13:13:48 |
| modified | [InstanceEdit:390413] D'Eustachio, P, 2009-02-06 21:28:38 |
| text | Peroxisomal glyceronephosphate O-acyltransferase (GNPAT) catalyzes the reaction of palmitoyl-CoA and DHAP to form 1-palmitoyl glycerone phosphate (1-palmitoyl dihydroxyacetone phosphate) and CoASH. The active form of the enzyme is one subunit of a heterotrimer with two molecules of the alkylglycerone phosphate synthase (AGPS) enzyme (Biermann et al. 1999). It was first purified and characterized biochemically by Ofman and Wanders (1994). Mutations in the GNPAT gene are associated with rhizomelic chondrodysplasia type 2 (Ofman et al. 1998, 2001). |
| (summation) | [Reaction:75879] palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH [Homo sapiens] |
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No pathways have been reviewed or authored by Peroxisomal glyceronephosphate O-acyltransferase (GNPAT) cat... (178382)
