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Details on Person Cytosolic deoxycytidine kinase (DCK) catalyzes the reactions...

Class:IdSummation:178258
_displayNameCytosolic deoxycytidine kinase (DCK) catalyzes the reactions...
_timestamp2010-02-01 16:44:05
created[InstanceEdit:179407] Gopinathrao, G, 2006-04-27 13:13:48
modified[InstanceEdit:500200] D'Eustachio, P, 2010-02-01
textCytosolic deoxycytidine kinase (DCK) catalyzes the reactions of deoxyadenosine and deoxyguanosine with ATP to form the corresponding nucleotide monophosphates and AMP, The enzyme is a dimer (Bohman and Eriksson 1988; Datta et al. 1989). While the enzyme can be found in nuclei of cultured cells expressing high levels of a tagged recombinant protein, its normal location appears to be cytosolic (Hatzis et al. 1998).
(summation)[Reaction:109671] deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) [Homo sapiens]
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