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Details on Person Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7

Class:IdLiteratureReference:178198
_displayNameChromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7
_timestamp2006-04-18 14:29:24
author[Person:178184] Tajima, Y
[Person:178164] Goto, K
[Person:178221] Yoshida, M
[Person:178229] Shinomiya, K
[Person:178209] Sekimoto, T
[Person:178142] Yoneda, Y
[Person:178191] Miyazono, K
[Person:178211] Imamura, T
created[InstanceEdit:178182] Jassal, B, 2006-04-18 14:28:42
journalJ Biol Chem
pages10716-21
pubMedIdentifier12519765
titleChromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7
volume278
year2003
(literatureReference)[Summation:2167915] SMAD7 binds to SMURF1 in the nucleus (Ebisawa et al. 2001, T...
[Summation:2167925] SMAD7:SMURF1 complex binds to XPO1 (CRM1) through a nuclear ...
[Summation:2169009] Smad7:SMURF1 complex, formed by exogenous expression of reco...
[Summation:2169010] Recombinant mouse Smad7 exogenously expressed in COS7 or HEK...
[Summation:2169015] XPO1 (CRM1) bound to Smad7:SMURF1 complex enables translocat...
[Summation:2169023] After SMAD7:SMURF1 complex binds to XPO1 (CRM1) through the ...
[Summation:2190603] TGF-beta receptor signaling is downregulated by proteasome a...
[Reaction:178215] SMAD7:SMURF1 complex is exported to the cytosol [Homo sapiens]
[Reaction:201475] I-Smad competes with R-Smad1/5/8 for type I receptor [Homo sapiens]
[Reaction:2167917] SMAD7 binds to SMURF1 [Homo sapiens]
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No pathways have been reviewed or authored by Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7 (178198)