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Details on Person Binding of PIK3 regulatory alpha subunit to GRB2:GAB1

Class:Id	Reaction:177931
_displayName	Binding of PIK3 regulatory alpha subunit to GRB2:GAB1
_doRelease	TRUE
_timestamp	2018-02-27 21:28:51
authored	[InstanceEdit:188408] Castagnoli, L, 2006-10-10 13:09:34
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:177921] Jassal, Bijay, 2006-04-11
edited	[InstanceEdit:1529121] Orlic-Milacic, Marija, 2011-08-25
figure	[Figure:179448] /figures/gab_grb2_binds_pi3k.jpg
input	[Complex:179849] GRB2:GAB1 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:74789] PIK3R1 [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:179884] Unique phosphorylation mechanism of Gab1 using PI 3-kinase as an adaptor protein
modified	[InstanceEdit:179435] Jassal, Bijay, 2006-04-28 [InstanceEdit:179447] Jassal, B, 2006-05-02 10:03:47 [InstanceEdit:179808] Jassal, Bijay, 2006-05-09 [InstanceEdit:188410] Jassal, B, 2006-10-12 13:36:05 [InstanceEdit:188431] Gopinathrao, G, 2006-10-12 14:53:00 [InstanceEdit:188528] Jassal, B, 2006-10-17 11:04:33 [InstanceEdit:188944] Gopinathrao, G, 2006-10-31 10:11:13 [InstanceEdit:188963] Gopinathrao, G, 2006-11-01 22:14:37 [InstanceEdit:189370] Gopinathrao, G, 2006-11-06 22:11:18 [InstanceEdit:192578] Gopinathrao, G, 2007-02-06 21:04:41 [InstanceEdit:193359] Gopinathrao, G, 2007-02-16 20:25:31 [InstanceEdit:212475] Jassal, Bijay, 2008-02-12 [InstanceEdit:215260] Gopinathrao, G, 2008-02-28 03:55:01 [InstanceEdit:1568624] Orlic-Milacic, Marija, 2011-09-06 [InstanceEdit:1583065] Orlic-Milacic, Marija, 2011-09-07 [InstanceEdit:9031667] Orlic-Milacic, Marija, 2017-12-01 [InstanceEdit:9038098] Orlic-Milacic, Marija, 2018-02-22 [InstanceEdit:9038407] Orlic-Milacic, Marija, 2018-02-26 [InstanceEdit:9038486] Orlic-Milacic, Marija, 2018-02-27 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Binding of PIK3 regulatory alpha subunit to GRB2:GAB1
output	[Complex:179864] GRB2:GAB1:PIK3R1 [cytosol] [Homo sapiens]
precedingEvent	[Reaction:177920] Binding of GRB2 to GAB1 [Homo sapiens]
releaseDate	2010-03-16
reviewed	[InstanceEdit:212476] Heldin, CH, 2008-02-12 09:44:02
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:359938] R-HSA-177931.3
summation	[Summation:188532] The Src homology 2 (SH2) domain of the phosphatidylinositol ...
(hasEvent)	[Pathway:5654689] PI-3K cascade:FGFR1 [Homo sapiens] [Pathway:5654695] PI-3K cascade:FGFR2 [Homo sapiens] [Pathway:5654710] PI-3K cascade:FGFR3 [Homo sapiens] [Pathway:5654720] PI-3K cascade:FGFR4 [Homo sapiens]
(precedingEvent)	[Reaction:5654592] Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 [Homo sapiens] [Reaction:5654594] Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 [Homo sapiens] [Reaction:5654612] Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 [Homo sapiens] [Reaction:5654620] Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 [Homo sapiens] [Reaction:5654637] Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 [Homo sapiens] [Reaction:5654641] Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 [Homo sapiens] [Reaction:5654659] Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 [Homo sapiens] [Reaction:5654667] Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9789519] Update Tracker - [Reaction:177931] Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 - v38:[modifyText]
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