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Details on Person Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR

Class:Id	LiteratureReference:177899
_displayName	Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR
_timestamp	2006-04-11 02:46:55
author	[Person:74573] Jiang, Z [Person:177894] Zamanian-Daryoush, M [Person:177897] Nie, H [Person:177891] Silva, AM [Person:168644] Williams, BR [Person:165941] Li, X
created	[InstanceEdit:177900] Gillespie, ME, 2006-04-11 02:46:41
journal	J Biol Chem
pages	16713-9
pubMedIdentifier	12609980
title	Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR
volume	278
year	2003
(literatureReference)	[Summation:847071] Phosphorylated TAK1 complexed with TRAF6-TAB1-TAB2/TAB3 leav... [Summation:937054] Phosphorylated TAK1 complexed with TRAF6-TAB1-TAB2/TAB3 leav... [Summation:1216488] It's believed that TAK1 dissociates from the membrane in to ... [Reaction:177690] Activated TLR3:TRIF:K63pUb-TRAF6 recruits TAK1complex [Homo sapiens] [Reaction:177692] Activation of recruited TAK1 within the activated TLR3 complex [Homo sapiens] [Reaction:847070] Phosphorylated TAK1 dissociates from the TLR3 receptor complex [Homo sapiens] [Reaction:921145] Activated chicken TAK1 dissociates from the activated TLR3 complex [Gallus gallus] [Reaction:937075] Phosphorylated TAK1 leaves activated TLR receptor complex [Homo sapiens] [Reaction:1008270] Activated TAK1 leaves endosome membrane [Gallus gallus] [Complex:177689] viral dsRNA:TLR3:TRIF:polyUb-TRAF6:TAK1:TAB1:TAB2/TAB3: free polyUb chain [endosome membrane] [Homo sapiens]
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No pathways have been reviewed or authored by Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR (177899)